LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 7 of 15: Mean cell count and mean growth rate across all replicates. - Dataset (ID:20243)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Mean Relative Cell Count Standard Error of the Mean for Relative Cell Count Mean Relative Growth Rate Standard Error of the Mean for Relative Growth Rate
SK-BR-3 Selumetinib
0.37
uM
LJP6
1.0097 0.0100 1.0142 0.0153
SK-BR-3 Sirolimus
0.37
uM
LJP6
0.6254 0.0189 0.3734 0.0590
SK-BR-3 Sorafenib
0.37
uM
LJP6
0.9730 0.0227 0.9555 0.0380
SK-BR-3 SU11274
0.37
uM
LJP5
1.0960 0.0244 1.1611 0.0424
SK-BR-3 Fedratinib
0.37
uM
LJP5
0.9535 0.0215 0.9267 0.0313
SK-BR-3 TGX221
0.37
uM
LJP5
0.9564 0.0108 0.9280 0.0176
SK-BR-3 Torin1
0.37
uM
LJP6
0.3646 0.0124 -0.0603 0.0757
SK-BR-3 Torin2
0.37
uM
LJP5
0.3135 0.0136 -0.1436 0.0666
SK-BR-3 Tozasertib
0.37
uM
LJP5
0.3447 0.0063 -0.0916 0.0583
SK-BR-3 Trametinib
0.37
uM
LJP5
0.7354 0.0329 0.5544 0.0722
SK-BR-3 TWS119
0.37
uM
LJP5
1.0571 0.0181 1.0974 0.0356
SK-BR-3 Vemurafenib
0.37
uM
LJP5
1.0348 0.0235 1.0625 0.0412
SK-BR-3 Withaferin A
0.37
uM
LJP5
0.5276 0.0612 0.2201 0.0865
SK-BR-3 Withaferin A
0.37
uM
LJP6
0.4590 0.0408 0.1013 0.0681
SK-BR-3 WYE-125132
0.37
uM
LJP6
0.3978 0.0166 -0.0065 0.0849
SK-BR-3 WZ3105
0.37
uM
LJP5
0.2586 0.0318 -0.2375 0.1041
SK-BR-3 XMD11-50
0.37
uM
LJP6
0.7435 0.0280 0.5681 0.0660
SK-BR-3 Y39983
0.37
uM
LJP6
0.8536 0.0413 0.7479 0.0823
SK-BR-3 YM 201636
0.37
uM
LJP5
1.0404 0.0282 1.0644 0.0426
SK-BR-3 ZSTK474
0.37
uM
LJP6
0.4834 0.0131 0.1396 0.0496
SK-BR-3 Afatinib
1.11
uM
LJP6
0.3645 0.0277 -0.0628 0.1010
SK-BR-3 Sigma A6730
1.11
uM
LJP5
0.7455 0.0185 0.5753 0.0407
SK-BR-3 Alvocidib
1.11
uM
LJP6
0.2178 0.0297 -0.3074 0.1167
SK-BR-3 AT-7519
1.11
uM
LJP6
0.2568 0.0277 -0.2384 0.0860
SK-BR-3 AZD 5438
1.11
uM
LJP6
0.3287 0.0259 -0.1168 0.0631