LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 Mitoxantrone
3.33
uM
LJP5
 72
hr
 1097 691 3769 0.1834 -0.1519
BT-20 Mitoxantrone
3.33
uM
LJP6
 72
hr
 1097 657 3769 0.1745 -0.1645
BT-20 MK2206
3.33
uM
LJP6
 72
hr
 1097 1707 3769 0.4528 0.2282
BT-20 Neratinib
3.33
uM
LJP5
 72
hr
 1097 1714 3769 0.4549 0.2310
BT-20 Nilotinib
3.33
uM
LJP5
 72
hr
 1097 3734 3769 0.9907 0.9868
BT-20 Nintedanib
3.33
uM
LJP6
 72
hr
 1097 2625 3769 0.6965 0.5718
BT-20 NU7441
3.33
uM
LJP5
 72
hr
 1097 3048 3769 0.8086 0.7300
BT-20 Dactolisib
3.33
uM
LJP5
 72
hr
 1097 1295 3769 0.3435 0.0740
BT-20 NVP-TAE684
3.33
uM
LJP6
 72
hr
 1097 1597 3769 0.4238 0.1871
BT-20 Palbociclib
3.33
uM
LJP6
 72
hr
 1097 1567 3769 0.4157 0.1758
BT-20 PD0325901
3.33
uM
LJP5
 72
hr
 1097 2253 3769 0.5978 0.4326
BT-20 PD0325901
3.33
uM
LJP6
 72
hr
 1097 2341 3769 0.6211 0.4656
BT-20 PD173074
3.33
uM
LJP6
 72
hr
 1097 4036 3769 1.0709 1.1000
BT-20 PD184352
3.33
uM
LJP5
 72
hr
 1097 3599 3769 0.9549 0.9363
BT-20 Pelitinib
3.33
uM
LJP5
 72
hr
 1097 2256 3769 0.5985 0.4336
BT-20 PF431396
3.33
uM
LJP5
 72
hr
 1097 1355 3769 0.3596 0.0967
BT-20 PF477736
3.33
uM
LJP5
 72
hr
 1097 3403 3769 0.9028 0.8628
BT-20 PF562271
3.33
uM
LJP6
 72
hr
 1097 1359 3769 0.3606 0.0981
BT-20 PHA-665752
3.33
uM
LJP5
 72
hr
 1097 3733 3769 0.9905 0.9866
BT-20 PHA-793887
3.33
uM
LJP6
 72
hr
 1097 920 3769 0.2442 -0.0662
BT-20 PI103
3.33
uM
LJP6
 72
hr
 1097 993 3769 0.2634 -0.0390
BT-20 PLX-4720
3.33
uM
LJP5
 72
hr
 1097 2550 3769 0.6767 0.5439
BT-20 QL-X-138
3.33
uM
LJP6
 72
hr
 1097 1562 3769 0.4146 0.1742
BT-20 QL-XII-47
3.33
uM
LJP6
 72
hr
 1097 719 3769 0.1909 -0.1413
BT-20 Radicicol
3.33
uM
LJP5
 72
hr
 1097 968 3769 0.2569 -0.0482