LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | PD173074 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 4694 | 4513 | 1.0401 | 1.0552 |
| MDA-MB-231 | PD173074 | 0.37 | uM | LJP6 | 72 | hr | 1235 | 5078 | 4513 | 1.1252 | 1.1724 |
| MDA-MB-231 | PD173074 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 4916 | 4513 | 1.0893 | 1.1230 |
| MDA-MB-231 | PD173074 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 4648 | 4513 | 1.0298 | 1.0410 |
| MDA-MB-231 | PD173074 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 1624 | 4513 | 0.3599 | 0.1185 |
| SK-BR-3 | Afatinib | 0.04 | uM | LJP6 | 72 | hr | 1401 | 1437 | 4223 | 0.3404 | 0.0127 |
| SK-BR-3 | Sigma A6730 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 3699 | 4223 | 0.8760 | 0.8144 |
| SK-BR-3 | Alvocidib | 0.04 | uM | LJP6 | 72 | hr | 1401 | 1580 | 4223 | 0.3743 | 0.0635 |
| SK-BR-3 | AT-7519 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 2511 | 4223 | 0.5948 | 0.3935 |
| SK-BR-3 | AZD 5438 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 3734 | 4223 | 0.8843 | 0.8268 |
| SK-BR-3 | AZD-6482 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4191 | 4223 | 0.9924 | 0.9886 |
| SK-BR-3 | AZD7762 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 1907 | 4223 | 0.4516 | 0.1793 |
| SK-BR-3 | AZD8055 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 1460 | 4223 | 0.3457 | 0.0207 |
| SK-BR-3 | AZD8330 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 3062 | 4223 | 0.7251 | 0.5886 |
| SK-BR-3 | Barasertib | 0.04 | uM | LJP5 | 72 | hr | 1401 | 1447 | 4223 | 0.3426 | 0.0161 |
| SK-BR-3 | BI-2536 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 1352 | 4223 | 0.3203 | -0.0173 |
| SK-BR-3 | BMS345541 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 4336 | 4223 | 1.0268 | 1.0401 |
| SK-BR-3 | SNS-032 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 2976 | 4223 | 0.7049 | 0.5583 |
| SK-BR-3 | GDC-0980 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 1941 | 4223 | 0.4596 | 0.1912 |
| SK-BR-3 | NVP-AEW541 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4161 | 4223 | 0.9854 | 0.9781 |
| SK-BR-3 | SB590885 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4804 | 4223 | 1.1377 | 1.2061 |
| SK-BR-3 | PIK-93 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4442 | 4223 | 1.0519 | 1.0777 |
| SK-BR-3 | KIN001-043 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 4174 | 4223 | 0.9884 | 0.9826 |
| SK-BR-3 | Alpelisib | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4129 | 4223 | 0.9778 | 0.9668 |
| SK-BR-3 | Luminespib | 0.04 | uM | LJP5 | 72 | hr | 1401 | 1644 | 4223 | 0.3893 | 0.0859 |