LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Afatinib | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1574 | 4223 | 0.3728 | 0.0612 |
| SK-BR-3 | Sigma A6730 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 3242 | 4223 | 0.7678 | 0.6525 |
| SK-BR-3 | Alvocidib | 1.11 | uM | LJP6 | 72 | hr | 1401 | 948 | 4223 | 0.2245 | -0.1607 |
| SK-BR-3 | AT-7519 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 953 | 4223 | 0.2257 | -0.1589 |
| SK-BR-3 | AZD 5438 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1208 | 4223 | 0.2862 | -0.0684 |
| SK-BR-3 | AZD-6482 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 3566 | 4223 | 0.8445 | 0.7672 |
| SK-BR-3 | AZD7762 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1112 | 4223 | 0.2634 | -0.1025 |
| SK-BR-3 | AZD8055 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1306 | 4223 | 0.3094 | -0.0336 |
| SK-BR-3 | AZD8330 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 3696 | 4223 | 0.8753 | 0.8133 |
| SK-BR-3 | Barasertib | 1.11 | uM | LJP5 | 72 | hr | 1401 | 1403 | 4223 | 0.3323 | 0.0006 |
| SK-BR-3 | BI-2536 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1232 | 4223 | 0.2918 | -0.0600 |
| SK-BR-3 | BMS345541 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 3166 | 4223 | 0.7499 | 0.6256 |
| SK-BR-3 | SNS-032 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1041 | 4223 | 0.2465 | -0.1278 |
| SK-BR-3 | GDC-0980 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 1403 | 4223 | 0.3322 | 0.0005 |
| SK-BR-3 | NVP-AEW541 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 3922 | 4223 | 0.9288 | 0.8934 |
| SK-BR-3 | SB590885 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 4714 | 4223 | 1.1163 | 1.1741 |
| SK-BR-3 | PIK-93 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 3491 | 4223 | 0.8268 | 0.7408 |
| SK-BR-3 | KIN001-043 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 3301 | 4223 | 0.7818 | 0.6734 |
| SK-BR-3 | Alpelisib | 1.11 | uM | LJP5 | 72 | hr | 1401 | 2916 | 4223 | 0.6905 | 0.5368 |
| SK-BR-3 | Luminespib | 1.11 | uM | LJP5 | 72 | hr | 1401 | 1582 | 4223 | 0.3746 | 0.0640 |
| SK-BR-3 | A443654 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1103 | 4223 | 0.2612 | -0.1058 |
| SK-BR-3 | OSI-027 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1700 | 4223 | 0.4026 | 0.1058 |
| SK-BR-3 | XMD11-85h | 1.11 | uM | LJP6 | 72 | hr | 1401 | 3704 | 4223 | 0.8771 | 0.8160 |
| SK-BR-3 | HG-6-64-01 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 3136 | 4223 | 0.7427 | 0.6150 |
| SK-BR-3 | WH-4-025 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 4406 | 4223 | 1.0433 | 1.0648 |