LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Mitoxantrone | 0.37 | uM | LJP5 | 72 | hr | 1401 | 1487 | 4223 | 0.3522 | 0.0304 |
| SK-BR-3 | Mitoxantrone | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1351 | 4223 | 0.3201 | -0.0177 |
| SK-BR-3 | MK2206 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 2683 | 4223 | 0.6355 | 0.4544 |
| SK-BR-3 | Neratinib | 0.37 | uM | LJP5 | 72 | hr | 1401 | 1408 | 4223 | 0.3335 | 0.0024 |
| SK-BR-3 | Nilotinib | 0.37 | uM | LJP5 | 72 | hr | 1401 | 4822 | 4223 | 1.1418 | 1.2123 |
| SK-BR-3 | Nintedanib | 0.37 | uM | LJP6 | 72 | hr | 1401 | 3918 | 4223 | 0.9278 | 0.8920 |
| SK-BR-3 | NU7441 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 3992 | 4223 | 0.9454 | 0.9183 |
| SK-BR-3 | Dactolisib | 0.37 | uM | LJP5 | 72 | hr | 1401 | 1347 | 4223 | 0.3190 | -0.0193 |
| SK-BR-3 | NVP-TAE684 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 3927 | 4223 | 0.9299 | 0.8951 |
| SK-BR-3 | Palbociclib | 0.37 | uM | LJP6 | 72 | hr | 1401 | 2845 | 4223 | 0.6738 | 0.5117 |
| SK-BR-3 | PD0325901 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 4082 | 4223 | 0.9668 | 0.9502 |
| SK-BR-3 | PD0325901 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 3694 | 4223 | 0.8748 | 0.8126 |
| SK-BR-3 | PD173074 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 4279 | 4223 | 1.0133 | 1.0199 |
| SK-BR-3 | PD184352 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 4471 | 4223 | 1.0589 | 1.0881 |
| SK-BR-3 | Pelitinib | 0.37 | uM | LJP5 | 72 | hr | 1401 | 1455 | 4223 | 0.3445 | 0.0190 |
| SK-BR-3 | PF431396 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 2164 | 4223 | 0.5124 | 0.2702 |
| SK-BR-3 | PF477736 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 1325 | 4223 | 0.3138 | -0.0270 |
| SK-BR-3 | PF562271 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 2942 | 4223 | 0.6967 | 0.5460 |
| SK-BR-3 | PHA-665752 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 4193 | 4223 | 0.9929 | 0.9893 |
| SK-BR-3 | PHA-793887 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1597 | 4223 | 0.3783 | 0.0695 |
| SK-BR-3 | PI103 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1778 | 4223 | 0.4210 | 0.1334 |
| SK-BR-3 | PLX-4720 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 3863 | 4223 | 0.9147 | 0.8724 |
| SK-BR-3 | QL-X-138 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 2319 | 4223 | 0.5491 | 0.3252 |
| SK-BR-3 | QL-XII-47 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 2085 | 4223 | 0.4937 | 0.2422 |
| SK-BR-3 | Radicicol | 0.37 | uM | LJP5 | 72 | hr | 1401 | 1712 | 4223 | 0.4054 | 0.1100 |