LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Afatinib | 1.11 | uM | LJP6 | 72 | hr | 962 | 1383 | 10605 | 0.1304 | 0.0436 |
| MCF 10A | Sigma A6730 | 1.11 | uM | LJP5 | 72 | hr | 962 | 9424 | 10605 | 0.8887 | 0.8776 |
| MCF 10A | Alvocidib | 1.11 | uM | LJP6 | 72 | hr | 962 | 212 | 10605 | 0.0200 | -0.0778 |
| MCF 10A | AT-7519 | 1.11 | uM | LJP6 | 72 | hr | 962 | 319 | 10605 | 0.0301 | -0.0667 |
| MCF 10A | AZD 5438 | 1.11 | uM | LJP6 | 72 | hr | 962 | 710 | 10605 | 0.0670 | -0.0261 |
| MCF 10A | AZD-6482 | 1.11 | uM | LJP5 | 72 | hr | 962 | 10023 | 10605 | 0.9452 | 0.9397 |
| MCF 10A | AZD7762 | 1.11 | uM | LJP6 | 72 | hr | 962 | 3756 | 10605 | 0.3542 | 0.2898 |
| MCF 10A | AZD8055 | 1.11 | uM | LJP6 | 72 | hr | 962 | 1540 | 10605 | 0.1452 | 0.0600 |
| MCF 10A | AZD8330 | 1.11 | uM | LJP5 | 72 | hr | 962 | 1630 | 10605 | 0.1537 | 0.0693 |
| MCF 10A | Barasertib | 1.11 | uM | LJP5 | 72 | hr | 962 | 1466 | 10605 | 0.1382 | 0.0522 |
| MCF 10A | BI-2536 | 1.11 | uM | LJP6 | 72 | hr | 962 | 963 | 10605 | 0.0908 | 0.0001 |
| MCF 10A | BMS345541 | 1.11 | uM | LJP6 | 72 | hr | 962 | 10222 | 10605 | 0.9639 | 0.9603 |
| MCF 10A | SNS-032 | 1.11 | uM | LJP6 | 72 | hr | 962 | 294 | 10605 | 0.0278 | -0.0692 |
| MCF 10A | GDC-0980 | 1.11 | uM | LJP5 | 72 | hr | 962 | 1397 | 10605 | 0.1317 | 0.0451 |
| MCF 10A | NVP-AEW541 | 1.11 | uM | LJP5 | 72 | hr | 962 | 9218 | 10605 | 0.8692 | 0.8562 |
| MCF 10A | SB590885 | 1.11 | uM | LJP5 | 72 | hr | 962 | 9627 | 10605 | 0.9078 | 0.8986 |
| MCF 10A | PIK-93 | 1.11 | uM | LJP5 | 72 | hr | 962 | 9343 | 10605 | 0.8811 | 0.8692 |
| MCF 10A | KIN001-043 | 1.11 | uM | LJP6 | 72 | hr | 962 | 9860 | 10605 | 0.9298 | 0.9228 |
| MCF 10A | Alpelisib | 1.11 | uM | LJP5 | 72 | hr | 962 | 9137 | 10605 | 0.8616 | 0.8478 |
| MCF 10A | Luminespib | 1.11 | uM | LJP5 | 72 | hr | 962 | 822 | 10605 | 0.0776 | -0.0145 |
| MCF 10A | A443654 | 1.11 | uM | LJP6 | 72 | hr | 962 | 674 | 10605 | 0.0636 | -0.0298 |
| MCF 10A | OSI-027 | 1.11 | uM | LJP6 | 72 | hr | 962 | 2181 | 10605 | 0.2057 | 0.1264 |
| MCF 10A | XMD11-85h | 1.11 | uM | LJP6 | 72 | hr | 962 | 10543 | 10605 | 0.9941 | 0.9936 |
| MCF 10A | HG-6-64-01 | 1.11 | uM | LJP6 | 72 | hr | 962 | 9196 | 10605 | 0.8672 | 0.8539 |
| MCF 10A | WH-4-025 | 1.11 | uM | LJP5 | 72 | hr | 962 | 4667 | 10605 | 0.4401 | 0.3842 |