LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Selumetinib | 0.37 | uM | LJP6 | 72 | hr | 1401 | 4343 | 4223 | 1.0286 | 1.0427 |
| SK-BR-3 | Sirolimus | 0.37 | uM | LJP6 | 72 | hr | 1401 | 2786 | 4223 | 0.6598 | 0.4908 |
| SK-BR-3 | Sorafenib | 0.37 | uM | LJP6 | 72 | hr | 1401 | 4190 | 4223 | 0.9922 | 0.9883 |
| SK-BR-3 | SU11274 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 4486 | 4223 | 1.0623 | 1.0933 |
| SK-BR-3 | Fedratinib | 0.37 | uM | LJP5 | 72 | hr | 1401 | 3870 | 4223 | 0.9164 | 0.8749 |
| SK-BR-3 | TGX221 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 4060 | 4223 | 0.9614 | 0.9422 |
| SK-BR-3 | Torin1 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1536 | 4223 | 0.3637 | 0.0477 |
| SK-BR-3 | Torin2 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 1242 | 4223 | 0.2941 | -0.0565 |
| SK-BR-3 | Tozasertib | 0.37 | uM | LJP5 | 72 | hr | 1401 | 1448 | 4223 | 0.3430 | 0.0167 |
| SK-BR-3 | Trametinib | 0.37 | uM | LJP5 | 72 | hr | 1401 | 3373 | 4223 | 0.7988 | 0.6988 |
| SK-BR-3 | TWS119 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 4448 | 4223 | 1.0534 | 1.0799 |
| SK-BR-3 | Vemurafenib | 0.37 | uM | LJP5 | 72 | hr | 1401 | 4175 | 4223 | 0.9888 | 0.9832 |
| SK-BR-3 | Withaferin A | 0.37 | uM | LJP5 | 72 | hr | 1401 | 2157 | 4223 | 0.5108 | 0.2679 |
| SK-BR-3 | Withaferin A | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1981 | 4223 | 0.4692 | 0.2055 |
| SK-BR-3 | WYE-125132 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1741 | 4223 | 0.4123 | 0.1203 |
| SK-BR-3 | WZ3105 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 1023 | 4223 | 0.2424 | -0.1339 |
| SK-BR-3 | XMD11-50 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 3374 | 4223 | 0.7990 | 0.6992 |
| SK-BR-3 | Y39983 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 3927 | 4223 | 0.9300 | 0.8952 |
| SK-BR-3 | YM 201636 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 4604 | 4223 | 1.0903 | 1.1351 |
| SK-BR-3 | ZSTK474 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1958 | 4223 | 0.4637 | 0.1973 |
| SK-BR-3 | Afatinib | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1574 | 4223 | 0.3728 | 0.0612 |
| SK-BR-3 | Sigma A6730 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 3242 | 4223 | 0.7678 | 0.6525 |
| SK-BR-3 | Alvocidib | 1.11 | uM | LJP6 | 72 | hr | 1401 | 948 | 4223 | 0.2245 | -0.1607 |
| SK-BR-3 | AT-7519 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 953 | 4223 | 0.2257 | -0.1589 |
| SK-BR-3 | AZD 5438 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1208 | 4223 | 0.2862 | -0.0684 |