LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A Sorafenib
0.12
uM
LJP6
 72
hr
 1694 11824 11155 1.0600 1.0707
MCF 10A Celastrol
0.04
uM
LJP6
 72
hr
 1694 11896 11155 1.0664 1.0783
MCF 10A Foretinib
0.04
uM
LJP5
 72
hr
 1694 11930 11155 1.0694 1.0819
MCF 10A Enzastaurin
10.0
uM
LJP5
 72
hr
 1694 12028 11155 1.0782 1.0922
MCF 10A PLX-4720
3.33
uM
LJP5
 72
hr
 1694 12034 11155 1.0788 1.0929
MCF 10A QL-X-138
0.12
uM
LJP6
 72
hr
 1694 12035 11155 1.0789 1.0930
MCF 10A Sorafenib
0.04
uM
LJP6
 72
hr
 1694 12063 11155 1.0814 1.0959
MCF 10A Sirolimus
0.04
uM
LJP6
 72
hr
 1694 12244 11155 1.0976 1.1151
MCF 10A QL-X-138
0.04
uM
LJP6
 72
hr
 1694 12300 11155 1.1026 1.1210
MCF 10A Sirolimus
0.12
uM
LJP6
 72
hr
 1694 12338 11155 1.1060 1.1250
MCF 10A Celastrol
0.12
uM
LJP6
 72
hr
 1694 12410 11155 1.1125 1.1326
MCF 10A Sirolimus
10.0
uM
LJP6
 72
hr
 1694 12441 11155 1.1152 1.1359
MCF 10A Sirolimus
1.11
uM
LJP6
 72
hr
 1694 12479 11155 1.1187 1.1399
MCF 10A Sirolimus
0.37
uM
LJP6
 72
hr
 1694 12534 11155 1.1236 1.1457
MCF 10A Sirolimus
3.33
uM
LJP6
 72
hr
 1694 12704 11155 1.1388 1.1636