LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T Selumetinib
0.12
uM
LJP6
 72
hr
 765 1742 3124 0.5575 0.4141
Hs 578T Sirolimus
0.12
uM
LJP6
 72
hr
 765 1899 3124 0.6079 0.4807
Hs 578T Sorafenib
0.12
uM
LJP6
 72
hr
 765 3587 3124 1.1480 1.1960
Hs 578T SU11274
0.12
uM
LJP5
 72
hr
 765 3171 3124 1.0151 1.0200
Hs 578T Fedratinib
0.12
uM
LJP5
 72
hr
 765 3148 3124 1.0075 1.0099
Hs 578T TGX221
0.12
uM
LJP5
 72
hr
 765 2904 3124 0.9294 0.9065
Hs 578T Torin1
0.12
uM
LJP6
 72
hr
 765 974 3124 0.3119 0.0888
Hs 578T Torin2
0.12
uM
LJP5
 72
hr
 765 813 3124 0.2602 0.0203
Hs 578T Tozasertib
0.12
uM
LJP5
 72
hr
 765 717 3124 0.2297 -0.0201
Hs 578T Trametinib
0.12
uM
LJP5
 72
hr
 765 1051 3124 0.3364 0.1212
Hs 578T TWS119
0.12
uM
LJP5
 72
hr
 765 3112 3124 0.9960 0.9947
Hs 578T Vemurafenib
0.12
uM
LJP5
 72
hr
 765 3257 3124 1.0426 1.0564
Hs 578T Withaferin A
0.12
uM
LJP5
 72
hr
 765 3180 3124 1.0179 1.0236
Hs 578T Withaferin A
0.12
uM
LJP6
 72
hr
 765 3026 3124 0.9687 0.9585
Hs 578T WYE-125132
0.12
uM
LJP6
 72
hr
 765 997 3124 0.3191 0.0983
Hs 578T WZ3105
0.12
uM
LJP5
 72
hr
 765 479 3124 0.1533 -0.1212
Hs 578T XMD11-50
0.12
uM
LJP6
 72
hr
 765 2921 3124 0.9350 0.9139
Hs 578T Y39983
0.12
uM
LJP6
 72
hr
 765 2537 3124 0.8120 0.7510
Hs 578T YM 201636
0.12
uM
LJP5
 72
hr
 765 3058 3124 0.9789 0.9721
Hs 578T ZSTK474
0.12
uM
LJP6
 72
hr
 765 2092 3124 0.6698 0.5627
Hs 578T Afatinib
0.37
uM
LJP6
 72
hr
 765 2883 3124 0.9229 0.8979
Hs 578T Sigma A6730
0.37
uM
LJP5
 72
hr
 765 2967 3124 0.9496 0.9332
Hs 578T Alvocidib
0.37
uM
LJP6
 72
hr
 765 384 3124 0.1230 -0.1614
Hs 578T AT-7519
0.37
uM
LJP6
 72
hr
 765 531 3124 0.1701 -0.0991
Hs 578T AZD 5438
0.37
uM
LJP6
 72
hr
 765 1360 3124 0.4353 0.2522