LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Afatinib | 10.0 | uM | LJP6 | 72 | hr | 2543 | 1731 | 5578 | 0.3104 | -0.2676 |
| SK-BR-3 | Sigma A6730 | 10.0 | uM | LJP5 | 72 | hr | 2543 | 3338 | 5578 | 0.5984 | 0.2619 |
| SK-BR-3 | Alvocidib | 10.0 | uM | LJP6 | 72 | hr | 2543 | 878 | 5578 | 0.1575 | -0.5485 |
| SK-BR-3 | AT-7519 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 697 | 5578 | 0.1251 | -0.6081 |
| SK-BR-3 | AZD 5438 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 733 | 5578 | 0.1315 | -0.5963 |
| SK-BR-3 | AZD-6482 | 10.0 | uM | LJP5 | 72 | hr | 2543 | 1693 | 5578 | 0.3036 | -0.2800 |
| SK-BR-3 | AZD7762 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 1226 | 5578 | 0.2198 | -0.4340 |
| SK-BR-3 | AZD8055 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 1586 | 5578 | 0.2844 | -0.3153 |
| SK-BR-3 | AZD8330 | 10.0 | uM | LJP5 | 72 | hr | 2543 | 4994 | 5578 | 0.8952 | 0.8074 |
| SK-BR-3 | Barasertib | 10.0 | uM | LJP5 | 72 | hr | 2543 | 2064 | 5578 | 0.3701 | -0.1578 |
| SK-BR-3 | BI-2536 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 1198 | 5578 | 0.2148 | -0.4433 |
| SK-BR-3 | BMS345541 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 933 | 5578 | 0.1673 | -0.5305 |
| SK-BR-3 | SNS-032 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 993 | 5578 | 0.1780 | -0.5108 |
| SK-BR-3 | GDC-0980 | 10.0 | uM | LJP5 | 72 | hr | 2543 | 1803 | 5578 | 0.3233 | -0.2439 |
| SK-BR-3 | NVP-AEW541 | 10.0 | uM | LJP5 | 72 | hr | 2543 | 3560 | 5578 | 0.6383 | 0.3351 |
| SK-BR-3 | SB590885 | 10.0 | uM | LJP5 | 72 | hr | 2543 | 1608 | 5578 | 0.2883 | -0.3081 |
| SK-BR-3 | PIK-93 | 10.0 | uM | LJP5 | 72 | hr | 2543 | 2171 | 5578 | 0.3893 | -0.1225 |
| SK-BR-3 | KIN001-043 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 2923 | 5578 | 0.5240 | 0.1251 |
| SK-BR-3 | Alpelisib | 10.0 | uM | LJP5 | 72 | hr | 2543 | 1938 | 5578 | 0.3475 | -0.1993 |
| SK-BR-3 | Luminespib | 10.0 | uM | LJP5 | 72 | hr | 2543 | 2194 | 5578 | 0.3933 | -0.1150 |
| SK-BR-3 | A443654 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 1031 | 5578 | 0.1849 | -0.4982 |
| SK-BR-3 | OSI-027 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 2120 | 5578 | 0.3801 | -0.1394 |
| SK-BR-3 | XMD11-85h | 10.0 | uM | LJP6 | 72 | hr | 2543 | 3696 | 5578 | 0.6626 | 0.3799 |
| SK-BR-3 | HG-6-64-01 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 1155 | 5578 | 0.2071 | -0.4573 |
| SK-BR-3 | WH-4-025 | 10.0 | uM | LJP5 | 72 | hr | 2543 | 1680 | 5578 | 0.3012 | -0.2845 |