LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
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BT-20 | TGX221 | 0.04 | uM | LJP5 | 72 | hr | 1657 | 5249 | 5505 | 0.9534 | 0.9334 |
BT-20 | Torin1 | 0.04 | uM | LJP6 | 72 | hr | 1657 | 2445 | 5505 | 0.4442 | 0.2047 |
BT-20 | Torin2 | 0.04 | uM | LJP5 | 72 | hr | 1657 | 1731 | 5505 | 0.3144 | 0.0190 |
BT-20 | Tozasertib | 0.04 | uM | LJP5 | 72 | hr | 1657 | 3346 | 5505 | 0.6077 | 0.4388 |
BT-20 | Trametinib | 0.04 | uM | LJP5 | 72 | hr | 1657 | 4042 | 5505 | 0.7342 | 0.6197 |
BT-20 | TWS119 | 0.04 | uM | LJP5 | 72 | hr | 1657 | 5554 | 5505 | 1.0088 | 1.0126 |
BT-20 | Vemurafenib | 0.04 | uM | LJP5 | 72 | hr | 1657 | 5732 | 5505 | 1.0412 | 1.0590 |
BT-20 | Withaferin A | 0.04 | uM | LJP5 | 72 | hr | 1657 | 5694 | 5505 | 1.0343 | 1.0490 |
BT-20 | Withaferin A | 0.04 | uM | LJP6 | 72 | hr | 1657 | 5684 | 5505 | 1.0324 | 1.0463 |
BT-20 | WYE-125132 | 0.04 | uM | LJP6 | 72 | hr | 1657 | 3100 | 5505 | 0.5632 | 0.3750 |
BT-20 | WZ3105 | 0.04 | uM | LJP5 | 72 | hr | 1657 | 2568 | 5505 | 0.4665 | 0.2367 |
BT-20 | XMD11-50 | 0.04 | uM | LJP6 | 72 | hr | 1657 | 4878 | 5505 | 0.8860 | 0.8369 |
BT-20 | Y39983 | 0.04 | uM | LJP6 | 72 | hr | 1657 | 5418 | 5505 | 0.9841 | 0.9773 |
BT-20 | YM 201636 | 0.04 | uM | LJP5 | 72 | hr | 1657 | 5842 | 5505 | 1.0611 | 1.0875 |
BT-20 | ZSTK474 | 0.04 | uM | LJP6 | 72 | hr | 1657 | 5377 | 5505 | 0.9768 | 0.9667 |
BT-20 | Afatinib | 0.12 | uM | LJP6 | 72 | hr | 1657 | 4514 | 5505 | 0.8199 | 0.7424 |
BT-20 | Sigma A6730 | 0.12 | uM | LJP5 | 72 | hr | 1657 | 4970 | 5505 | 0.9028 | 0.8610 |
BT-20 | Alvocidib | 0.12 | uM | LJP6 | 72 | hr | 1657 | 1396 | 5505 | 0.2537 | -0.0678 |
BT-20 | AT-7519 | 0.12 | uM | LJP6 | 72 | hr | 1657 | 4313 | 5505 | 0.7834 | 0.6901 |
BT-20 | AZD 5438 | 0.12 | uM | LJP6 | 72 | hr | 1657 | 3913 | 5505 | 0.7107 | 0.5861 |
BT-20 | AZD-6482 | 0.12 | uM | LJP5 | 72 | hr | 1657 | 5004 | 5505 | 0.9089 | 0.8697 |
BT-20 | AZD7762 | 0.12 | uM | LJP6 | 72 | hr | 1657 | 5352 | 5505 | 0.9722 | 0.9602 |
BT-20 | AZD8055 | 0.12 | uM | LJP6 | 72 | hr | 1657 | 2341 | 5505 | 0.4253 | 0.1777 |
BT-20 | AZD8330 | 0.12 | uM | LJP5 | 72 | hr | 1657 | 4338 | 5505 | 0.7880 | 0.6966 |
BT-20 | Barasertib | 0.12 | uM | LJP5 | 72 | hr | 1657 | 4476 | 5505 | 0.8130 | 0.7325 |