LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 TGX221
0.04
uM
LJP5
72
hr
1657 5249 5505 0.9534 0.9334
BT-20 Torin1
0.04
uM
LJP6
72
hr
1657 2445 5505 0.4442 0.2047
BT-20 Torin2
0.04
uM
LJP5
72
hr
1657 1731 5505 0.3144 0.0190
BT-20 Tozasertib
0.04
uM
LJP5
72
hr
1657 3346 5505 0.6077 0.4388
BT-20 Trametinib
0.04
uM
LJP5
72
hr
1657 4042 5505 0.7342 0.6197
BT-20 TWS119
0.04
uM
LJP5
72
hr
1657 5554 5505 1.0088 1.0126
BT-20 Vemurafenib
0.04
uM
LJP5
72
hr
1657 5732 5505 1.0412 1.0590
BT-20 Withaferin A
0.04
uM
LJP5
72
hr
1657 5694 5505 1.0343 1.0490
BT-20 Withaferin A
0.04
uM
LJP6
72
hr
1657 5684 5505 1.0324 1.0463
BT-20 WYE-125132
0.04
uM
LJP6
72
hr
1657 3100 5505 0.5632 0.3750
BT-20 WZ3105
0.04
uM
LJP5
72
hr
1657 2568 5505 0.4665 0.2367
BT-20 XMD11-50
0.04
uM
LJP6
72
hr
1657 4878 5505 0.8860 0.8369
BT-20 Y39983
0.04
uM
LJP6
72
hr
1657 5418 5505 0.9841 0.9773
BT-20 YM 201636
0.04
uM
LJP5
72
hr
1657 5842 5505 1.0611 1.0875
BT-20 ZSTK474
0.04
uM
LJP6
72
hr
1657 5377 5505 0.9768 0.9667
BT-20 Afatinib
0.12
uM
LJP6
72
hr
1657 4514 5505 0.8199 0.7424
BT-20 Sigma A6730
0.12
uM
LJP5
72
hr
1657 4970 5505 0.9028 0.8610
BT-20 Alvocidib
0.12
uM
LJP6
72
hr
1657 1396 5505 0.2537 -0.0678
BT-20 AT-7519
0.12
uM
LJP6
72
hr
1657 4313 5505 0.7834 0.6901
BT-20 AZD 5438
0.12
uM
LJP6
72
hr
1657 3913 5505 0.7107 0.5861
BT-20 AZD-6482
0.12
uM
LJP5
72
hr
1657 5004 5505 0.9089 0.8697
BT-20 AZD7762
0.12
uM
LJP6
72
hr
1657 5352 5505 0.9722 0.9602
BT-20 AZD8055
0.12
uM
LJP6
72
hr
1657 2341 5505 0.4253 0.1777
BT-20 AZD8330
0.12
uM
LJP5
72
hr
1657 4338 5505 0.7880 0.6966
BT-20 Barasertib
0.12
uM
LJP5
72
hr
1657 4476 5505 0.8130 0.7325