LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | TWS119 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 3778 | 3694 | 1.0229 | 1.0382 |
| SK-BR-3 | Vemurafenib | 1.11 | uM | LJP5 | 72 | hr | 1476 | 3752 | 3694 | 1.0157 | 1.0261 |
| SK-BR-3 | Withaferin A | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1392 | 3694 | 0.3768 | -0.0382 |
| SK-BR-3 | Withaferin A | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1234 | 3694 | 0.3341 | -0.1095 |
| SK-BR-3 | WYE-125132 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1617 | 3694 | 0.4378 | 0.0634 |
| SK-BR-3 | WZ3105 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1235 | 3694 | 0.3343 | -0.1090 |
| SK-BR-3 | XMD11-50 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 2480 | 3694 | 0.6714 | 0.4526 |
| SK-BR-3 | Y39983 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 2751 | 3694 | 0.7448 | 0.5748 |
| SK-BR-3 | YM 201636 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 3299 | 3694 | 0.8932 | 0.8220 |
| SK-BR-3 | ZSTK474 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1575 | 3694 | 0.4264 | 0.0443 |
| SK-BR-3 | Afatinib | 3.33 | uM | LJP6 | 72 | hr | 1476 | 1484 | 3694 | 0.4017 | 0.0033 |
| SK-BR-3 | Sigma A6730 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 2723 | 3694 | 0.7372 | 0.5622 |
| SK-BR-3 | Alvocidib | 3.33 | uM | LJP6 | 72 | hr | 1476 | 1080 | 3694 | 0.2925 | -0.1788 |
| SK-BR-3 | AT-7519 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 983 | 3694 | 0.2661 | -0.2227 |
| SK-BR-3 | AZD 5438 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 1083 | 3694 | 0.2934 | -0.1773 |
| SK-BR-3 | AZD-6482 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 2344 | 3694 | 0.6346 | 0.3913 |
| SK-BR-3 | AZD7762 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 1004 | 3694 | 0.2720 | -0.2129 |
| SK-BR-3 | AZD8055 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 1322 | 3694 | 0.3580 | -0.0696 |
| SK-BR-3 | AZD8330 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 3127 | 3694 | 0.8466 | 0.7444 |
| SK-BR-3 | Barasertib | 3.33 | uM | LJP5 | 72 | hr | 1476 | 1392 | 3694 | 0.3770 | -0.0379 |
| SK-BR-3 | BI-2536 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 1426 | 3694 | 0.3860 | -0.0229 |
| SK-BR-3 | BMS345541 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 1820 | 3694 | 0.4929 | 0.1551 |
| SK-BR-3 | SNS-032 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 843 | 3694 | 0.2282 | -0.2858 |
| SK-BR-3 | GDC-0980 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 1498 | 3694 | 0.4055 | 0.0096 |
| SK-BR-3 | NVP-AEW541 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 3906 | 3694 | 1.0576 | 1.0959 |