LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
SK-BR-3 PHA-793887
10.0
uM
LJP6
 72
hr
 1476 1049 3694 0.2840 -0.1929
SK-BR-3 PI103
10.0
uM
LJP6
 72
hr
 1476 1389 3694 0.3761 -0.0394
SK-BR-3 QL-X-138
10.0
uM
LJP6
 72
hr
 1476 1220 3694 0.3304 -0.1156
SK-BR-3 QL-XII-47
10.0
uM
LJP6
 72
hr
 1476 659 3694 0.1786 -0.3685
SK-BR-3 Radicicol
10.0
uM
LJP6
 72
hr
 1476 1124 3694 0.3043 -0.1591
SK-BR-3 Saracatinib
10.0
uM
LJP6
 72
hr
 1476 1968 3694 0.5329 0.2219
SK-BR-3 Selumetinib
10.0
uM
LJP6
 72
hr
 1476 3522 3694 0.9534 0.9224
SK-BR-3 Sirolimus
10.0
uM
LJP6
 72
hr
 1476 2203 3694 0.5964 0.3276
SK-BR-3 Sorafenib
10.0
uM
LJP6
 72
hr
 1476 1730 3694 0.4685 0.1145
SK-BR-3 Torin1
10.0
uM
LJP6
 72
hr
 1476 1116 3694 0.3022 -0.1625
SK-BR-3 Withaferin A
10.0
uM
LJP6
 72
hr
 1476 989 3694 0.2677 -0.2200
SK-BR-3 WYE-125132
10.0
uM
LJP6
 72
hr
 1476 1510 3694 0.4089 0.0152
SK-BR-3 XMD11-50
10.0
uM
LJP6
 72
hr
 1476 1647 3694 0.4459 0.0768
SK-BR-3 Y39983
10.0
uM
LJP6
 72
hr
 1476 1243 3694 0.3366 -0.1053
BT-20 Afatinib
0.04
uM
LJP6
 72
hr
 1657 3980 5505 0.7230 0.6036