LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
BT-20 Vemurafenib
3.33
uM
LJP5
 3
C14
 72
hr
 1097 3440 3769 0.9126 0.8767
BT-20 Withaferin A
3.33
uM
LJP5
 1
G14
 72
hr
 1097 602 3769 0.1597 -0.1853
BT-20 Withaferin A
3.33
uM
LJP5
 2
G14
 72
hr
 1097 544 3769 0.1443 -0.2070
BT-20 Withaferin A
3.33
uM
LJP5
 3
G14
 72
hr
 1097 560 3769 0.1486 -0.2011
BT-20 Withaferin A
3.33
uM
LJP6
 1
G14
 72
hr
 1097 539 3769 0.1430 -0.2089
BT-20 Withaferin A
3.33
uM
LJP6
 2
G14
 72
hr
 1097 574 3769 0.1523 -0.1958
BT-20 Withaferin A
3.33
uM
LJP6
 3
G14
 72
hr
 1097 494 3769 0.1311 -0.2258
BT-20 WYE-125132
3.33
uM
LJP6
 1
L08
 72
hr
 1097 1170 3769 0.3104 0.0272
BT-20 WYE-125132
3.33
uM
LJP6
 2
L08
 72
hr
 1097 1219 3769 0.3234 0.0456
BT-20 WYE-125132
3.33
uM
LJP6
 3
L08
 72
hr
 1097 1111 3769 0.2947 0.0051
BT-20 WZ3105
3.33
uM
LJP5
 1
D20
 72
hr
 1097 657 3769 0.1743 -0.1648
BT-20 WZ3105
3.33
uM
LJP5
 2
D20
 72
hr
 1097 740 3769 0.1963 -0.1337
BT-20 WZ3105
3.33
uM
LJP5
 3
D20
 72
hr
 1097 766 3769 0.2032 -0.1240
BT-20 XMD11-50
3.33
uM
LJP6
 1
P08
 72
hr
 1097 2007 3769 0.5324 0.3404
BT-20 XMD11-50
3.33
uM
LJP6
 2
P08
 72
hr
 1097 1975 3769 0.5239 0.3285
BT-20 XMD11-50
3.33
uM
LJP6
 3
P08
 72
hr
 1097 2191 3769 0.5812 0.4093
BT-20 Y39983
3.33
uM
LJP6
 1
P02
 72
hr
 1097 2883 3769 0.7648 0.6683
BT-20 Y39983
3.33
uM
LJP6
 2
P02
 72
hr
 1097 2671 3769 0.7086 0.5889
BT-20 Y39983
3.33
uM
LJP6
 3
P02
 72
hr
 1097 3156 3769 0.8372 0.7704
BT-20 YM 201636
3.33
uM
LJP5
 1
N08
 72
hr
 1097 2291 3769 0.6078 0.4467
BT-20 YM 201636
3.33
uM
LJP5
 2
N08
 72
hr
 1097 2436 3769 0.6462 0.5010
BT-20 YM 201636
3.33
uM
LJP5
 3
N08
 72
hr
 1097 2158 3769 0.5725 0.3969
BT-20 ZSTK474
3.33
uM
LJP6
 1
M14
 72
hr
 1097 1006 3769 0.2669 -0.0341
BT-20 ZSTK474
3.33
uM
LJP6
 2
M14
 72
hr
 1097 994 3769 0.2637 -0.0386
BT-20 ZSTK474
3.33
uM
LJP6
 3
M14
 72
hr
 1097 1151 3769 0.3053 0.0201