LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
BT-20 YM 201636
1.11
uM
LJP5
2
N09
72
hr
1097 3043 3769 0.8073 0.7281
BT-20 YM 201636
1.11
uM
LJP5
3
N09
72
hr
1097 2797 3769 0.7420 0.6361
BT-20 ZSTK474
1.11
uM
LJP6
1
M15
72
hr
1097 1231 3769 0.3266 0.0500
BT-20 ZSTK474
1.11
uM
LJP6
2
M15
72
hr
1097 1180 3769 0.3130 0.0310
BT-20 ZSTK474
1.11
uM
LJP6
3
M15
72
hr
1097 1201 3769 0.3186 0.0388
BT-20 Afatinib
3.33
uM
LJP6
1
G20
72
hr
1097 3204 3769 0.8500 0.7884
BT-20 Afatinib
3.33
uM
LJP6
2
G20
72
hr
1097 3264 3769 0.8659 0.8108
BT-20 Afatinib
3.33
uM
LJP6
3
G20
72
hr
1097 3292 3769 0.8733 0.8213
BT-20 Sigma A6730
3.33
uM
LJP5
1
B20
72
hr
1097 3275 3769 0.8688 0.8149
BT-20 Sigma A6730
3.33
uM
LJP5
2
B20
72
hr
1097 3417 3769 0.9065 0.8681
BT-20 Sigma A6730
3.33
uM
LJP5
3
B20
72
hr
1097 3310 3769 0.8781 0.8280
BT-20 Alvocidib
3.33
uM
LJP6
1
A14
72
hr
1097 680 3769 0.1804 -0.1561
BT-20 Alvocidib
3.33
uM
LJP6
2
A14
72
hr
1097 646 3769 0.1714 -0.1689
BT-20 Alvocidib
3.33
uM
LJP6
3
A14
72
hr
1097 580 3769 0.1539 -0.1936
BT-20 AT-7519
3.33
uM
LJP6
1
K02
72
hr
1097 445 3769 0.1181 -0.2441
BT-20 AT-7519
3.33
uM
LJP6
2
K02
72
hr
1097 705 3769 0.1870 -0.1468
BT-20 AT-7519
3.33
uM
LJP6
3
K02
72
hr
1097 470 3769 0.1247 -0.2347
BT-20 AZD 5438
3.33
uM
LJP6
1
J02
72
hr
1097 796 3769 0.2112 -0.1127
BT-20 AZD 5438
3.33
uM
LJP6
2
J02
72
hr
1097 774 3769 0.2053 -0.1210
BT-20 AZD 5438
3.33
uM
LJP6
3
J02
72
hr
1097 715 3769 0.1897 -0.1430
BT-20 AZD-6482
3.33
uM
LJP5
1
I02
72
hr
1097 1295 3769 0.3435 0.0740
BT-20 AZD-6482
3.33
uM
LJP5
2
I02
72
hr
1097 1578 3769 0.4186 0.1799
BT-20 AZD-6482
3.33
uM
LJP5
3
I02
72
hr
1097 1455 3769 0.3860 0.1339
BT-20 AZD7762
3.33
uM
LJP6
1
L02
72
hr
1097 714 3769 0.1894 -0.1434
BT-20 AZD7762
3.33
uM
LJP6
2
L02
72
hr
1097 794 3769 0.2106 -0.1135