LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
SK-BR-3 Dovitinib
10.0
uM
LJP5
3
E19
72
hr
1401 2039 4223 0.4828 0.2259
SK-BR-3 Enzastaurin
10.0
uM
LJP5
1
D13
72
hr
1401 4049 4223 0.9588 0.9383
SK-BR-3 Enzastaurin
10.0
uM
LJP5
2
D13
72
hr
1401 4094 4223 0.9694 0.9543
SK-BR-3 Enzastaurin
10.0
uM
LJP5
3
D13
72
hr
1401 4485 4223 1.0620 1.0928
SK-BR-3 Erlotinib
10.0
uM
LJP5
1
M19
72
hr
1401 1831 4223 0.4336 0.1522
SK-BR-3 Erlotinib
10.0
uM
LJP5
2
M19
72
hr
1401 2190 4223 0.5186 0.2795
SK-BR-3 Erlotinib
10.0
uM
LJP5
3
M19
72
hr
1401 2159 4223 0.5112 0.2685
SK-BR-3 Foretinib
10.0
uM
LJP5
1
H07
72
hr
1401 1406 4223 0.3329 0.0016
SK-BR-3 Foretinib
10.0
uM
LJP5
2
H07
72
hr
1401 1264 4223 0.2993 -0.0487
SK-BR-3 Foretinib
10.0
uM
LJP5
3
H07
72
hr
1401 1386 4223 0.3282 -0.0055
SK-BR-3 R406
10.0
uM
LJP6
1
C13
72
hr
1401 3004 4223 0.7113 0.5679
SK-BR-3 R406
10.0
uM
LJP6
2
C13
72
hr
1401 3017 4223 0.7144 0.5726
SK-BR-3 R406
10.0
uM
LJP6
3
C13
72
hr
1401 3081 4223 0.7296 0.5952
SK-BR-3 Pictilisib
10.0
uM
LJP6
1
D19
72
hr
1401 1542 4223 0.3651 0.0498
SK-BR-3 Pictilisib
10.0
uM
LJP6
2
D19
72
hr
1401 1382 4223 0.3273 -0.0069
SK-BR-3 Pictilisib
10.0
uM
LJP6
3
D19
72
hr
1401 1565 4223 0.3706 0.0579
SK-BR-3 Gefitinib
10.0
uM
LJP6
1
N07
72
hr
1401 1900 4223 0.4499 0.1767
SK-BR-3 Gefitinib
10.0
uM
LJP6
2
N07
72
hr
1401 1715 4223 0.4061 0.1111
SK-BR-3 Gefitinib
10.0
uM
LJP6
3
N07
72
hr
1401 1700 4223 0.4026 0.1058
SK-BR-3 Geldanamycin
10.0
uM
LJP5
1
O01
72
hr
1401 519 4223 0.1229 -0.3128
SK-BR-3 Geldanamycin
10.0
uM
LJP5
2
O01
72
hr
1401 1027 4223 0.2432 -0.1327
SK-BR-3 Geldanamycin
10.0
uM
LJP5
3
O01
72
hr
1401 1199 4223 0.2839 -0.0718
SK-BR-3 Geldanamycin
10.0
uM
LJP6
1
O01
72
hr
1401 547 4223 0.1295 -0.3029
SK-BR-3 Geldanamycin
10.0
uM
LJP6
2
O01
72
hr
1401 1000 4223 0.2368 -0.1423
SK-BR-3 Geldanamycin
10.0
uM
LJP6
3
O01
72
hr
1401 771 4223 0.1826 -0.2235