LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SK-BR-3 | YM 201636 | 1.11 | uM | LJP5 | 2 | N09 | 72 | hr | 1401 | 3847 | 4223 | 0.9109 | 0.8667 |
SK-BR-3 | YM 201636 | 1.11 | uM | LJP5 | 3 | N09 | 72 | hr | 1401 | 4305 | 4223 | 1.0194 | 1.0290 |
SK-BR-3 | ZSTK474 | 1.11 | uM | LJP6 | 1 | M15 | 72 | hr | 1401 | 1772 | 4223 | 0.4196 | 0.1313 |
SK-BR-3 | ZSTK474 | 1.11 | uM | LJP6 | 2 | M15 | 72 | hr | 1401 | 1707 | 4223 | 0.4042 | 0.1083 |
SK-BR-3 | ZSTK474 | 1.11 | uM | LJP6 | 3 | M15 | 72 | hr | 1401 | 1645 | 4223 | 0.3895 | 0.0863 |
SK-BR-3 | Afatinib | 3.33 | uM | LJP6 | 1 | G20 | 72 | hr | 1401 | 1325 | 4223 | 0.3138 | -0.0271 |
SK-BR-3 | Afatinib | 3.33 | uM | LJP6 | 2 | G20 | 72 | hr | 1401 | 1587 | 4223 | 0.3758 | 0.0657 |
SK-BR-3 | Afatinib | 3.33 | uM | LJP6 | 3 | G20 | 72 | hr | 1401 | 1740 | 4223 | 0.4120 | 0.1200 |
SK-BR-3 | Sigma A6730 | 3.33 | uM | LJP5 | 1 | B20 | 72 | hr | 1401 | 2820 | 4223 | 0.6678 | 0.5027 |
SK-BR-3 | Sigma A6730 | 3.33 | uM | LJP5 | 2 | B20 | 72 | hr | 1401 | 3080 | 4223 | 0.7293 | 0.5949 |
SK-BR-3 | Sigma A6730 | 3.33 | uM | LJP5 | 3 | B20 | 72 | hr | 1401 | 3263 | 4223 | 0.7727 | 0.6597 |
SK-BR-3 | Alvocidib | 3.33 | uM | LJP6 | 1 | A14 | 72 | hr | 1401 | 1032 | 4223 | 0.2444 | -0.1310 |
SK-BR-3 | Alvocidib | 3.33 | uM | LJP6 | 2 | A14 | 72 | hr | 1401 | 854 | 4223 | 0.2022 | -0.1941 |
SK-BR-3 | Alvocidib | 3.33 | uM | LJP6 | 3 | A14 | 72 | hr | 1401 | 825 | 4223 | 0.1954 | -0.2043 |
SK-BR-3 | AT-7519 | 3.33 | uM | LJP6 | 1 | K02 | 72 | hr | 1401 | 584 | 4223 | 0.1383 | -0.2897 |
SK-BR-3 | AT-7519 | 3.33 | uM | LJP6 | 2 | K02 | 72 | hr | 1401 | 872 | 4223 | 0.2065 | -0.1877 |
SK-BR-3 | AT-7519 | 3.33 | uM | LJP6 | 3 | K02 | 72 | hr | 1401 | 677 | 4223 | 0.1603 | -0.2568 |
SK-BR-3 | AZD 5438 | 3.33 | uM | LJP6 | 1 | J02 | 72 | hr | 1401 | 1141 | 4223 | 0.2702 | -0.0923 |
SK-BR-3 | AZD 5438 | 3.33 | uM | LJP6 | 2 | J02 | 72 | hr | 1401 | 973 | 4223 | 0.2304 | -0.1519 |
SK-BR-3 | AZD 5438 | 3.33 | uM | LJP6 | 3 | J02 | 72 | hr | 1401 | 1024 | 4223 | 0.2425 | -0.1338 |
SK-BR-3 | AZD-6482 | 3.33 | uM | LJP5 | 1 | I02 | 72 | hr | 1401 | 1587 | 4223 | 0.3758 | 0.0657 |
SK-BR-3 | AZD-6482 | 3.33 | uM | LJP5 | 2 | I02 | 72 | hr | 1401 | 2971 | 4223 | 0.7035 | 0.5562 |
SK-BR-3 | AZD-6482 | 3.33 | uM | LJP5 | 3 | I02 | 72 | hr | 1401 | 3636 | 4223 | 0.8610 | 0.7919 |
SK-BR-3 | AZD7762 | 3.33 | uM | LJP6 | 1 | L02 | 72 | hr | 1401 | 868 | 4223 | 0.2055 | -0.1891 |
SK-BR-3 | AZD7762 | 3.33 | uM | LJP6 | 2 | L02 | 72 | hr | 1401 | 1263 | 4223 | 0.2991 | -0.0491 |