LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
BT-20 Torin1
0.12
uM
LJP6
 3
O17
 72
hr
 1097 1324 3769 0.3512 0.0849
BT-20 Torin2
0.12
uM
LJP5
 1
I23
 72
hr
 1097 930 3769 0.2467 -0.0626
BT-20 Torin2
0.12
uM
LJP5
 2
I23
 72
hr
 1097 920 3769 0.2441 -0.0663
BT-20 Torin2
0.12
uM
LJP5
 3
I23
 72
hr
 1097 930 3769 0.2467 -0.0626
BT-20 Tozasertib
0.12
uM
LJP5
 1
B17
 72
hr
 1097 1303 3769 0.3457 0.0770
BT-20 Tozasertib
0.12
uM
LJP5
 2
B17
 72
hr
 1097 1374 3769 0.3645 0.1036
BT-20 Tozasertib
0.12
uM
LJP5
 3
B17
 72
hr
 1097 1492 3769 0.3958 0.1477
BT-20 Trametinib
0.12
uM
LJP5
 1
P23
 72
hr
 1097 2963 3769 0.7860 0.6982
BT-20 Trametinib
0.12
uM
LJP5
 2
P23
 72
hr
 1097 2973 3769 0.7887 0.7019
BT-20 Trametinib
0.12
uM
LJP5
 3
P23
 72
hr
 1097 3187 3769 0.8455 0.7820
BT-20 TWS119
0.12
uM
LJP5
 1
M05
 72
hr
 1097 3687 3769 0.9781 0.9691
BT-20 TWS119
0.12
uM
LJP5
 2
M05
 72
hr
 1097 3867 3769 1.0259 1.0365
BT-20 TWS119
0.12
uM
LJP5
 3
M05
 72
hr
 1097 3717 3769 0.9861 0.9803
BT-20 Vemurafenib
0.12
uM
LJP5
 1
C17
 72
hr
 1097 3713 3769 0.9850 0.9788
BT-20 Vemurafenib
0.12
uM
LJP5
 2
C17
 72
hr
 1097 3651 3769 0.9686 0.9556
BT-20 Vemurafenib
0.12
uM
LJP5
 3
C17
 72
hr
 1097 3665 3769 0.9723 0.9609
BT-20 Withaferin A
0.12
uM
LJP5
 1
G17
 72
hr
 1097 4198 3769 1.1137 1.1603
BT-20 Withaferin A
0.12
uM
LJP5
 2
G17
 72
hr
 1097 4359 3769 1.1564 1.2206
BT-20 Withaferin A
0.12
uM
LJP5
 3
G17
 72
hr
 1097 4152 3769 1.1015 1.1431
BT-20 Withaferin A
0.12
uM
LJP6
 1
G17
 72
hr
 1097 3742 3769 0.9927 0.9897
BT-20 Withaferin A
0.12
uM
LJP6
 2
G17
 72
hr
 1097 3628 3769 0.9625 0.9470
BT-20 Withaferin A
0.12
uM
LJP6
 3
G17
 72
hr
 1097 3271 3769 0.8678 0.8134
BT-20 WYE-125132
0.12
uM
LJP6
 1
L11
 72
hr
 1097 1400 3769 0.3714 0.1133
BT-20 WYE-125132
0.12
uM
LJP6
 2
L11
 72
hr
 1097 1434 3769 0.3804 0.1260
BT-20 WYE-125132
0.12
uM
LJP6
 3
L11
 72
hr
 1097 1363 3769 0.3616 0.0994