LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
BT-20 Neratinib
0.12
uM
LJP5
2
A17
72
hr
1097 2721 3769 0.7218 0.6076
BT-20 Neratinib
0.12
uM
LJP5
3
A17
72
hr
1097 2749 3769 0.7293 0.6181
BT-20 Nilotinib
0.12
uM
LJP5
1
N17
72
hr
1097 3967 3769 1.0524 1.0739
BT-20 Nilotinib
0.12
uM
LJP5
2
N17
72
hr
1097 4377 3769 1.1612 1.2273
BT-20 Nilotinib
0.12
uM
LJP5
3
N17
72
hr
1097 3664 3769 0.9720 0.9605
BT-20 Nintedanib
0.12
uM
LJP6
1
H05
72
hr
1097 3145 3769 0.8343 0.7663
BT-20 Nintedanib
0.12
uM
LJP6
2
H05
72
hr
1097 3513 3769 0.9319 0.9040
BT-20 Nintedanib
0.12
uM
LJP6
3
H05
72
hr
1097 3511 3769 0.9314 0.9033
BT-20 NU7441
0.12
uM
LJP5
1
C11
72
hr
1097 3850 3769 1.0213 1.0301
BT-20 NU7441
0.12
uM
LJP5
2
C11
72
hr
1097 3649 3769 0.9680 0.9549
BT-20 NU7441
0.12
uM
LJP5
3
C11
72
hr
1097 3763 3769 0.9983 0.9976
BT-20 Dactolisib
0.12
uM
LJP5
1
M17
72
hr
1097 1192 3769 0.3162 0.0355
BT-20 Dactolisib
0.12
uM
LJP5
2
M17
72
hr
1097 1059 3769 0.2809 -0.0143
BT-20 Dactolisib
0.12
uM
LJP5
3
M17
72
hr
1097 1043 3769 0.2767 -0.0203
BT-20 NVP-TAE684
0.12
uM
LJP6
1
K17
72
hr
1097 3545 3769 0.9404 0.9160
BT-20 NVP-TAE684
0.12
uM
LJP6
2
K17
72
hr
1097 3589 3769 0.9521 0.9324
BT-20 NVP-TAE684
0.12
uM
LJP6
3
K17
72
hr
1097 3905 3769 1.0359 1.0507
BT-20 Palbociclib
0.12
uM
LJP6
1
E17
72
hr
1097 2026 3769 0.5375 0.3476
BT-20 Palbociclib
0.12
uM
LJP6
2
E17
72
hr
1097 1978 3769 0.5247 0.3296
BT-20 Palbociclib
0.12
uM
LJP6
3
E17
72
hr
1097 1873 3769 0.4969 0.2903
BT-20 PD0325901
0.12
uM
LJP5
1
C05
72
hr
1097 3049 3769 0.8089 0.7304
BT-20 PD0325901
0.12
uM
LJP5
2
C05
72
hr
1097 2794 3769 0.7412 0.6349
BT-20 PD0325901
0.12
uM
LJP5
3
C05
72
hr
1097 3440 3769 0.9126 0.8767
BT-20 PD0325901
0.12
uM
LJP6
1
E05
72
hr
1097 3062 3769 0.8123 0.7352
BT-20 PD0325901
0.12
uM
LJP6
2
E05
72
hr
1097 3193 3769 0.8471 0.7843