LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
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BT-20 | Neratinib | 0.12 | uM | LJP5 | 2 | A17 | 72 | hr | 1097 | 2721 | 3769 | 0.7218 | 0.6076 |
BT-20 | Neratinib | 0.12 | uM | LJP5 | 3 | A17 | 72 | hr | 1097 | 2749 | 3769 | 0.7293 | 0.6181 |
BT-20 | Nilotinib | 0.12 | uM | LJP5 | 1 | N17 | 72 | hr | 1097 | 3967 | 3769 | 1.0524 | 1.0739 |
BT-20 | Nilotinib | 0.12 | uM | LJP5 | 2 | N17 | 72 | hr | 1097 | 4377 | 3769 | 1.1612 | 1.2273 |
BT-20 | Nilotinib | 0.12 | uM | LJP5 | 3 | N17 | 72 | hr | 1097 | 3664 | 3769 | 0.9720 | 0.9605 |
BT-20 | Nintedanib | 0.12 | uM | LJP6 | 1 | H05 | 72 | hr | 1097 | 3145 | 3769 | 0.8343 | 0.7663 |
BT-20 | Nintedanib | 0.12 | uM | LJP6 | 2 | H05 | 72 | hr | 1097 | 3513 | 3769 | 0.9319 | 0.9040 |
BT-20 | Nintedanib | 0.12 | uM | LJP6 | 3 | H05 | 72 | hr | 1097 | 3511 | 3769 | 0.9314 | 0.9033 |
BT-20 | NU7441 | 0.12 | uM | LJP5 | 1 | C11 | 72 | hr | 1097 | 3850 | 3769 | 1.0213 | 1.0301 |
BT-20 | NU7441 | 0.12 | uM | LJP5 | 2 | C11 | 72 | hr | 1097 | 3649 | 3769 | 0.9680 | 0.9549 |
BT-20 | NU7441 | 0.12 | uM | LJP5 | 3 | C11 | 72 | hr | 1097 | 3763 | 3769 | 0.9983 | 0.9976 |
BT-20 | Dactolisib | 0.12 | uM | LJP5 | 1 | M17 | 72 | hr | 1097 | 1192 | 3769 | 0.3162 | 0.0355 |
BT-20 | Dactolisib | 0.12 | uM | LJP5 | 2 | M17 | 72 | hr | 1097 | 1059 | 3769 | 0.2809 | -0.0143 |
BT-20 | Dactolisib | 0.12 | uM | LJP5 | 3 | M17 | 72 | hr | 1097 | 1043 | 3769 | 0.2767 | -0.0203 |
BT-20 | NVP-TAE684 | 0.12 | uM | LJP6 | 1 | K17 | 72 | hr | 1097 | 3545 | 3769 | 0.9404 | 0.9160 |
BT-20 | NVP-TAE684 | 0.12 | uM | LJP6 | 2 | K17 | 72 | hr | 1097 | 3589 | 3769 | 0.9521 | 0.9324 |
BT-20 | NVP-TAE684 | 0.12 | uM | LJP6 | 3 | K17 | 72 | hr | 1097 | 3905 | 3769 | 1.0359 | 1.0507 |
BT-20 | Palbociclib | 0.12 | uM | LJP6 | 1 | E17 | 72 | hr | 1097 | 2026 | 3769 | 0.5375 | 0.3476 |
BT-20 | Palbociclib | 0.12 | uM | LJP6 | 2 | E17 | 72 | hr | 1097 | 1978 | 3769 | 0.5247 | 0.3296 |
BT-20 | Palbociclib | 0.12 | uM | LJP6 | 3 | E17 | 72 | hr | 1097 | 1873 | 3769 | 0.4969 | 0.2903 |
BT-20 | PD0325901 | 0.12 | uM | LJP5 | 1 | C05 | 72 | hr | 1097 | 3049 | 3769 | 0.8089 | 0.7304 |
BT-20 | PD0325901 | 0.12 | uM | LJP5 | 2 | C05 | 72 | hr | 1097 | 2794 | 3769 | 0.7412 | 0.6349 |
BT-20 | PD0325901 | 0.12 | uM | LJP5 | 3 | C05 | 72 | hr | 1097 | 3440 | 3769 | 0.9126 | 0.8767 |
BT-20 | PD0325901 | 0.12 | uM | LJP6 | 1 | E05 | 72 | hr | 1097 | 3062 | 3769 | 0.8123 | 0.7352 |
BT-20 | PD0325901 | 0.12 | uM | LJP6 | 2 | E05 | 72 | hr | 1097 | 3193 | 3769 | 0.8471 | 0.7843 |