LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
BT-20 Withaferin A
0.04
uM
LJP6
2
G18
72
hr
1097 4023 3769 1.0672 1.0948
BT-20 Withaferin A
0.04
uM
LJP6
3
G18
72
hr
1097 3715 3769 0.9855 0.9796
BT-20 WYE-125132
0.04
uM
LJP6
1
L12
72
hr
1097 1782 3769 0.4727 0.2562
BT-20 WYE-125132
0.04
uM
LJP6
2
L12
72
hr
1097 1706 3769 0.4526 0.2278
BT-20 WYE-125132
0.04
uM
LJP6
3
L12
72
hr
1097 1813 3769 0.4810 0.2678
BT-20 WZ3105
0.04
uM
LJP5
1
D24
72
hr
1097 1723 3769 0.4571 0.2342
BT-20 WZ3105
0.04
uM
LJP5
2
D24
72
hr
1097 1675 3769 0.4444 0.2162
BT-20 WZ3105
0.04
uM
LJP5
3
D24
72
hr
1097 1986 3769 0.5269 0.3326
BT-20 XMD11-50
0.04
uM
LJP6
1
P12
72
hr
1097 2797 3769 0.7420 0.6361
BT-20 XMD11-50
0.04
uM
LJP6
2
P12
72
hr
1097 2931 3769 0.7776 0.6862
BT-20 XMD11-50
0.04
uM
LJP6
3
P12
72
hr
1097 3216 3769 0.8532 0.7929
BT-20 Y39983
0.04
uM
LJP6
1
P06
72
hr
1097 3397 3769 0.9012 0.8606
BT-20 Y39983
0.04
uM
LJP6
2
P06
72
hr
1097 3283 3769 0.8709 0.8179
BT-20 Y39983
0.04
uM
LJP6
3
P06
72
hr
1097 3586 3769 0.9513 0.9313
BT-20 YM 201636
0.04
uM
LJP5
1
N12
72
hr
1097 3717 3769 0.9861 0.9803
BT-20 YM 201636
0.04
uM
LJP5
2
N12
72
hr
1097 4561 3769 1.2100 1.2962
BT-20 YM 201636
0.04
uM
LJP5
3
N12
72
hr
1097 4260 3769 1.1301 1.1835
BT-20 ZSTK474
0.04
uM
LJP6
1
M18
72
hr
1097 3469 3769 0.9203 0.8875
BT-20 ZSTK474
0.04
uM
LJP6
2
M18
72
hr
1097 3510 3769 0.9312 0.9029
BT-20 ZSTK474
0.04
uM
LJP6
3
M18
72
hr
1097 3483 3769 0.9240 0.8928
BT-20 Afatinib
0.12
uM
LJP6
1
G23
72
hr
1097 3096 3769 0.8213 0.7480
BT-20 Afatinib
0.12
uM
LJP6
2
G23
72
hr
1097 2895 3769 0.7680 0.6727
BT-20 Afatinib
0.12
uM
LJP6
3
G23
72
hr
1097 3106 3769 0.8240 0.7517
BT-20 Sigma A6730
0.12
uM
LJP5
1
B23
72
hr
1097 3257 3769 0.8640 0.8082
BT-20 Sigma A6730
0.12
uM
LJP5
2
B23
72
hr
1097 3250 3769 0.8622 0.8056