LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SK-BR-3 | PIK-93 | 10.0 | uM | LJP5 | 3 | K13 | 72 | hr | 1476 | 1545 | 3694 | 0.4182 | 0.0308 |
SK-BR-3 | KIN001-043 | 10.0 | uM | LJP6 | 1 | C07 | 72 | hr | 1476 | 1668 | 3694 | 0.4515 | 0.0863 |
SK-BR-3 | KIN001-043 | 10.0 | uM | LJP6 | 2 | C07 | 72 | hr | 1476 | 1789 | 3694 | 0.4843 | 0.1408 |
SK-BR-3 | KIN001-043 | 10.0 | uM | LJP6 | 3 | C07 | 72 | hr | 1476 | 1711 | 3694 | 0.4632 | 0.1057 |
SK-BR-3 | Alpelisib | 10.0 | uM | LJP5 | 1 | N01 | 72 | hr | 1476 | 1062 | 3694 | 0.2875 | -0.1870 |
SK-BR-3 | Alpelisib | 10.0 | uM | LJP5 | 2 | N01 | 72 | hr | 1476 | 1220 | 3694 | 0.3303 | -0.1158 |
SK-BR-3 | Alpelisib | 10.0 | uM | LJP5 | 3 | N01 | 72 | hr | 1476 | 1263 | 3694 | 0.3419 | -0.0964 |
SK-BR-3 | Luminespib | 10.0 | uM | LJP5 | 1 | H13 | 72 | hr | 1476 | 1574 | 3694 | 0.4261 | 0.0439 |
SK-BR-3 | Luminespib | 10.0 | uM | LJP5 | 2 | H13 | 72 | hr | 1476 | 1459 | 3694 | 0.3950 | -0.0080 |
SK-BR-3 | Luminespib | 10.0 | uM | LJP5 | 3 | H13 | 72 | hr | 1476 | 1544 | 3694 | 0.4180 | 0.0303 |
SK-BR-3 | A443654 | 10.0 | uM | LJP6 | 1 | I19 | 72 | hr | 1476 | 907 | 3694 | 0.2455 | -0.2569 |
SK-BR-3 | A443654 | 10.0 | uM | LJP6 | 2 | I19 | 72 | hr | 1476 | 1137 | 3694 | 0.3078 | -0.1532 |
SK-BR-3 | A443654 | 10.0 | uM | LJP6 | 3 | I19 | 72 | hr | 1476 | 920 | 3694 | 0.2491 | -0.2511 |
SK-BR-3 | OSI-027 | 10.0 | uM | LJP6 | 1 | E07 | 72 | hr | 1476 | 1795 | 3694 | 0.4859 | 0.1435 |
SK-BR-3 | OSI-027 | 10.0 | uM | LJP6 | 2 | E07 | 72 | hr | 1476 | 1569 | 3694 | 0.4247 | 0.0416 |
SK-BR-3 | OSI-027 | 10.0 | uM | LJP6 | 3 | E07 | 72 | hr | 1476 | 1586 | 3694 | 0.4293 | 0.0493 |
SK-BR-3 | XMD11-85h | 10.0 | uM | LJP6 | 1 | P19 | 72 | hr | 1476 | 2395 | 3694 | 0.6483 | 0.4141 |
SK-BR-3 | XMD11-85h | 10.0 | uM | LJP6 | 2 | P19 | 72 | hr | 1476 | 2425 | 3694 | 0.6565 | 0.4277 |
SK-BR-3 | XMD11-85h | 10.0 | uM | LJP6 | 3 | P19 | 72 | hr | 1476 | 2178 | 3694 | 0.5896 | 0.3163 |
SK-BR-3 | HG-6-64-01 | 10.0 | uM | LJP6 | 1 | M01 | 72 | hr | 1476 | 877 | 3694 | 0.2374 | -0.2705 |
SK-BR-3 | HG-6-64-01 | 10.0 | uM | LJP6 | 2 | M01 | 72 | hr | 1476 | 854 | 3694 | 0.2312 | -0.2808 |
SK-BR-3 | HG-6-64-01 | 10.0 | uM | LJP6 | 3 | M01 | 72 | hr | 1476 | 698 | 3694 | 0.1890 | -0.3512 |
SK-BR-3 | WH-4-025 | 10.0 | uM | LJP5 | 1 | O07 | 72 | hr | 1476 | 1182 | 3694 | 0.3200 | -0.1329 |
SK-BR-3 | WH-4-025 | 10.0 | uM | LJP5 | 2 | O07 | 72 | hr | 1476 | 1170 | 3694 | 0.3167 | -0.1383 |
SK-BR-3 | WH-4-025 | 10.0 | uM | LJP5 | 3 | O07 | 72 | hr | 1476 | 1213 | 3694 | 0.3284 | -0.1189 |