LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | GDC-0980 | 1.11 | uM | LJP5 | 2 | K21 | 72 | hr | 1476 | 1262 | 3694 | 0.3416 | -0.0968 |
| SK-BR-3 | GDC-0980 | 1.11 | uM | LJP5 | 3 | K21 | 72 | hr | 1476 | 1459 | 3694 | 0.3950 | -0.0080 |
| SK-BR-3 | NVP-AEW541 | 1.11 | uM | LJP5 | 1 | E15 | 72 | hr | 1476 | 3732 | 3694 | 1.0103 | 1.0171 |
| SK-BR-3 | NVP-AEW541 | 1.11 | uM | LJP5 | 2 | E15 | 72 | hr | 1476 | 4145 | 3694 | 1.1221 | 1.2034 |
| SK-BR-3 | NVP-AEW541 | 1.11 | uM | LJP5 | 3 | E15 | 72 | hr | 1476 | 4013 | 3694 | 1.0863 | 1.1438 |
| SK-BR-3 | SB590885 | 1.11 | uM | LJP5 | 1 | L15 | 72 | hr | 1476 | 4060 | 3694 | 1.0991 | 1.1650 |
| SK-BR-3 | SB590885 | 1.11 | uM | LJP5 | 2 | L15 | 72 | hr | 1476 | 4258 | 3694 | 1.1527 | 1.2543 |
| SK-BR-3 | SB590885 | 1.11 | uM | LJP5 | 3 | L15 | 72 | hr | 1476 | 4435 | 3694 | 1.2006 | 1.3342 |
| SK-BR-3 | PIK-93 | 1.11 | uM | LJP5 | 1 | K15 | 72 | hr | 1476 | 3874 | 3694 | 1.0487 | 1.0812 |
| SK-BR-3 | PIK-93 | 1.11 | uM | LJP5 | 2 | K15 | 72 | hr | 1476 | 3584 | 3694 | 0.9702 | 0.9504 |
| SK-BR-3 | PIK-93 | 1.11 | uM | LJP5 | 3 | K15 | 72 | hr | 1476 | 3799 | 3694 | 1.0284 | 1.0473 |
| SK-BR-3 | KIN001-043 | 1.11 | uM | LJP6 | 1 | C09 | 72 | hr | 1476 | 2987 | 3694 | 0.8086 | 0.6811 |
| SK-BR-3 | KIN001-043 | 1.11 | uM | LJP6 | 2 | C09 | 72 | hr | 1476 | 3072 | 3694 | 0.8316 | 0.7195 |
| SK-BR-3 | KIN001-043 | 1.11 | uM | LJP6 | 3 | C09 | 72 | hr | 1476 | 2967 | 3694 | 0.8032 | 0.6721 |
| SK-BR-3 | Alpelisib | 1.11 | uM | LJP5 | 1 | N03 | 72 | hr | 1476 | 2520 | 3694 | 0.6822 | 0.4705 |
| SK-BR-3 | Alpelisib | 1.11 | uM | LJP5 | 2 | N03 | 72 | hr | 1476 | 2604 | 3694 | 0.7049 | 0.5084 |
| SK-BR-3 | Alpelisib | 1.11 | uM | LJP5 | 3 | N03 | 72 | hr | 1476 | 2603 | 3694 | 0.7047 | 0.5079 |
| SK-BR-3 | Luminespib | 1.11 | uM | LJP5 | 1 | H15 | 72 | hr | 1476 | 1573 | 3694 | 0.4258 | 0.0434 |
| SK-BR-3 | Luminespib | 1.11 | uM | LJP5 | 2 | H15 | 72 | hr | 1476 | 1615 | 3694 | 0.4372 | 0.0624 |
| SK-BR-3 | Luminespib | 1.11 | uM | LJP5 | 3 | H15 | 72 | hr | 1476 | 1677 | 3694 | 0.4540 | 0.0903 |
| SK-BR-3 | A443654 | 1.11 | uM | LJP6 | 1 | I21 | 72 | hr | 1476 | 1205 | 3694 | 0.3262 | -0.1225 |
| SK-BR-3 | A443654 | 1.11 | uM | LJP6 | 2 | I21 | 72 | hr | 1476 | 1192 | 3694 | 0.3227 | -0.1284 |
| SK-BR-3 | A443654 | 1.11 | uM | LJP6 | 3 | I21 | 72 | hr | 1476 | 1190 | 3694 | 0.3221 | -0.1293 |
| SK-BR-3 | OSI-027 | 1.11 | uM | LJP6 | 1 | E09 | 72 | hr | 1476 | 1765 | 3694 | 0.4778 | 0.1300 |
| SK-BR-3 | OSI-027 | 1.11 | uM | LJP6 | 2 | E09 | 72 | hr | 1476 | 1830 | 3694 | 0.4954 | 0.1593 |