LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
SK-BR-3 R406
0.37
uM
LJP6
1
C16
72
hr
1476 3848 3694 1.0417 1.0694
SK-BR-3 R406
0.37
uM
LJP6
2
C16
72
hr
1476 3786 3694 1.0249 1.0415
SK-BR-3 R406
0.37
uM
LJP6
3
C16
72
hr
1476 3844 3694 1.0406 1.0676
SK-BR-3 Pictilisib
0.37
uM
LJP6
1
D22
72
hr
1476 1730 3694 0.4683 0.1142
SK-BR-3 Pictilisib
0.37
uM
LJP6
2
D22
72
hr
1476 1809 3694 0.4897 0.1499
SK-BR-3 Pictilisib
0.37
uM
LJP6
3
D22
72
hr
1476 1949 3694 0.5276 0.2130
SK-BR-3 Gefitinib
0.37
uM
LJP6
1
N10
72
hr
1476 2132 3694 0.5771 0.2955
SK-BR-3 Gefitinib
0.37
uM
LJP6
2
N10
72
hr
1476 2902 3694 0.7856 0.6428
SK-BR-3 Gefitinib
0.37
uM
LJP6
3
N10
72
hr
1476 2616 3694 0.7082 0.5138
SK-BR-3 Geldanamycin
0.37
uM
LJP5
1
O04
72
hr
1476 1554 3694 0.4207 0.0349
SK-BR-3 Geldanamycin
0.37
uM
LJP5
2
O04
72
hr
1476 1424 3694 0.3855 -0.0238
SK-BR-3 Geldanamycin
0.37
uM
LJP5
3
O04
72
hr
1476 1364 3694 0.3692 -0.0508
SK-BR-3 Geldanamycin
0.37
uM
LJP6
1
O04
72
hr
1476 1277 3694 0.3457 -0.0901
SK-BR-3 Geldanamycin
0.37
uM
LJP6
2
O04
72
hr
1476 1376 3694 0.3725 -0.0454
SK-BR-3 Geldanamycin
0.37
uM
LJP6
3
O04
72
hr
1476 1274 3694 0.3449 -0.0914
SK-BR-3 GSK1059615
0.37
uM
LJP5
1
E04
72
hr
1476 2882 3694 0.7802 0.6338
SK-BR-3 GSK1059615
0.37
uM
LJP5
2
E04
72
hr
1476 2718 3694 0.7358 0.5598
SK-BR-3 GSK1059615
0.37
uM
LJP5
3
E04
72
hr
1476 2429 3694 0.6575 0.4295
SK-BR-3 GSK1059615
0.37
uM
LJP6
1
C04
72
hr
1476 2186 3694 0.5918 0.3199
SK-BR-3 GSK1059615
0.37
uM
LJP6
2
C04
72
hr
1476 2349 3694 0.6359 0.3934
SK-BR-3 GSK1059615
0.37
uM
LJP6
3
C04
72
hr
1476 2322 3694 0.6286 0.3812
SK-BR-3 GSK1904529A
0.37
uM
LJP6
1
H22
72
hr
1476 3246 3694 0.8787 0.7979
SK-BR-3 GSK1904529A
0.37
uM
LJP6
2
H22
72
hr
1476 3662 3694 0.9913 0.9856
SK-BR-3 GSK1904529A
0.37
uM
LJP6
3
H22
72
hr
1476 3883 3694 1.0511 1.0852
SK-BR-3 Omipalisib
0.37
uM
LJP6
1
N04
72
hr
1476 1256 3694 0.3400 -0.0995