LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | XMD11-50 | 0.37 | uM | LJP6 | 3 | P10 | 72 | hr | 1476 | 2612 | 3694 | 0.7071 | 0.5120 |
| SK-BR-3 | Y39983 | 0.37 | uM | LJP6 | 1 | P04 | 72 | hr | 1476 | 3298 | 3694 | 0.8928 | 0.8214 |
| SK-BR-3 | Y39983 | 0.37 | uM | LJP6 | 2 | P04 | 72 | hr | 1476 | 3162 | 3694 | 0.8560 | 0.7601 |
| SK-BR-3 | Y39983 | 0.37 | uM | LJP6 | 3 | P04 | 72 | hr | 1476 | 2879 | 3694 | 0.7794 | 0.6324 |
| SK-BR-3 | YM 201636 | 0.37 | uM | LJP5 | 1 | N10 | 72 | hr | 1476 | 3907 | 3694 | 1.0576 | 1.0960 |
| SK-BR-3 | YM 201636 | 0.37 | uM | LJP5 | 2 | N10 | 72 | hr | 1476 | 3616 | 3694 | 0.9789 | 0.9648 |
| SK-BR-3 | YM 201636 | 0.37 | uM | LJP5 | 3 | N10 | 72 | hr | 1476 | 3478 | 3694 | 0.9415 | 0.9026 |
| SK-BR-3 | ZSTK474 | 0.37 | uM | LJP6 | 1 | M16 | 72 | hr | 1476 | 1796 | 3694 | 0.4862 | 0.1440 |
| SK-BR-3 | ZSTK474 | 0.37 | uM | LJP6 | 2 | M16 | 72 | hr | 1476 | 2104 | 3694 | 0.5696 | 0.2829 |
| SK-BR-3 | ZSTK474 | 0.37 | uM | LJP6 | 3 | M16 | 72 | hr | 1476 | 1732 | 3694 | 0.4689 | 0.1151 |
| SK-BR-3 | Afatinib | 1.11 | uM | LJP6 | 1 | G21 | 72 | hr | 1476 | 1384 | 3694 | 0.3747 | -0.0418 |
| SK-BR-3 | Afatinib | 1.11 | uM | LJP6 | 2 | G21 | 72 | hr | 1476 | 1558 | 3694 | 0.4218 | 0.0367 |
| SK-BR-3 | Afatinib | 1.11 | uM | LJP6 | 3 | G21 | 72 | hr | 1476 | 1576 | 3694 | 0.4266 | 0.0448 |
| SK-BR-3 | Sigma A6730 | 1.11 | uM | LJP5 | 1 | B21 | 72 | hr | 1476 | 2635 | 3694 | 0.7133 | 0.5224 |
| SK-BR-3 | Sigma A6730 | 1.11 | uM | LJP5 | 2 | B21 | 72 | hr | 1476 | 2526 | 3694 | 0.6838 | 0.4732 |
| SK-BR-3 | Sigma A6730 | 1.11 | uM | LJP5 | 3 | B21 | 72 | hr | 1476 | 2693 | 3694 | 0.7290 | 0.5485 |
| SK-BR-3 | Alvocidib | 1.11 | uM | LJP6 | 1 | A15 | 72 | hr | 1476 | 1054 | 3694 | 0.2853 | -0.1906 |
| SK-BR-3 | Alvocidib | 1.11 | uM | LJP6 | 2 | A15 | 72 | hr | 1476 | 1095 | 3694 | 0.2964 | -0.1722 |
| SK-BR-3 | Alvocidib | 1.11 | uM | LJP6 | 3 | A15 | 72 | hr | 1476 | 794 | 3694 | 0.2149 | -0.3079 |
| SK-BR-3 | AT-7519 | 1.11 | uM | LJP6 | 1 | K03 | 72 | hr | 1476 | 1194 | 3694 | 0.3232 | -0.1275 |
| SK-BR-3 | AT-7519 | 1.11 | uM | LJP6 | 2 | K03 | 72 | hr | 1476 | 1048 | 3694 | 0.2837 | -0.1934 |
| SK-BR-3 | AT-7519 | 1.11 | uM | LJP6 | 3 | K03 | 72 | hr | 1476 | 1216 | 3694 | 0.3292 | -0.1176 |
| SK-BR-3 | AZD 5438 | 1.11 | uM | LJP6 | 1 | J03 | 72 | hr | 1476 | 1199 | 3694 | 0.3246 | -0.1253 |
| SK-BR-3 | AZD 5438 | 1.11 | uM | LJP6 | 2 | J03 | 72 | hr | 1476 | 1593 | 3694 | 0.4312 | 0.0524 |
| SK-BR-3 | AZD 5438 | 1.11 | uM | LJP6 | 3 | J03 | 72 | hr | 1476 | 1371 | 3694 | 0.3711 | -0.0477 |