LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Tozasertib | 0.37 | uM | LJP5 | 2 | B16 | 72 | hr | 1476 | 1182 | 3694 | 0.3200 | -0.1329 |
| SK-BR-3 | Tozasertib | 0.37 | uM | LJP5 | 3 | B16 | 72 | hr | 1476 | 1223 | 3694 | 0.3311 | -0.1144 |
| SK-BR-3 | Trametinib | 0.37 | uM | LJP5 | 1 | P22 | 72 | hr | 1476 | 2517 | 3694 | 0.6814 | 0.4692 |
| SK-BR-3 | Trametinib | 0.37 | uM | LJP5 | 2 | P22 | 72 | hr | 1476 | 2495 | 3694 | 0.6754 | 0.4592 |
| SK-BR-3 | Trametinib | 0.37 | uM | LJP5 | 3 | P22 | 72 | hr | 1476 | 2618 | 3694 | 0.7087 | 0.5147 |
| SK-BR-3 | TWS119 | 0.37 | uM | LJP5 | 1 | M04 | 72 | hr | 1476 | 3976 | 3694 | 1.0763 | 1.1272 |
| SK-BR-3 | TWS119 | 0.37 | uM | LJP5 | 2 | M04 | 72 | hr | 1476 | 3786 | 3694 | 1.0249 | 1.0415 |
| SK-BR-3 | TWS119 | 0.37 | uM | LJP5 | 3 | M04 | 72 | hr | 1476 | 3628 | 3694 | 0.9821 | 0.9702 |
| SK-BR-3 | Vemurafenib | 0.37 | uM | LJP5 | 1 | C16 | 72 | hr | 1476 | 3506 | 3694 | 0.9491 | 0.9152 |
| SK-BR-3 | Vemurafenib | 0.37 | uM | LJP5 | 2 | C16 | 72 | hr | 1476 | 3970 | 3694 | 1.0747 | 1.1245 |
| SK-BR-3 | Vemurafenib | 0.37 | uM | LJP5 | 3 | C16 | 72 | hr | 1476 | 4155 | 3694 | 1.1248 | 1.2079 |
| SK-BR-3 | Withaferin A | 0.37 | uM | LJP5 | 1 | G16 | 72 | hr | 1476 | 1695 | 3694 | 0.4589 | 0.0984 |
| SK-BR-3 | Withaferin A | 0.37 | uM | LJP5 | 2 | G16 | 72 | hr | 1476 | 1597 | 3694 | 0.4323 | 0.0542 |
| SK-BR-3 | Withaferin A | 0.37 | uM | LJP5 | 3 | G16 | 72 | hr | 1476 | 1485 | 3694 | 0.4020 | 0.0037 |
| SK-BR-3 | Withaferin A | 0.37 | uM | LJP6 | 1 | G16 | 72 | hr | 1476 | 1262 | 3694 | 0.3416 | -0.0968 |
| SK-BR-3 | Withaferin A | 0.37 | uM | LJP6 | 2 | G16 | 72 | hr | 1476 | 1603 | 3694 | 0.4339 | 0.0570 |
| SK-BR-3 | Withaferin A | 0.37 | uM | LJP6 | 3 | G16 | 72 | hr | 1476 | 1388 | 3694 | 0.3757 | -0.0400 |
| SK-BR-3 | WYE-125132 | 0.37 | uM | LJP6 | 1 | L10 | 72 | hr | 1476 | 1095 | 3694 | 0.2964 | -0.1722 |
| SK-BR-3 | WYE-125132 | 0.37 | uM | LJP6 | 2 | L10 | 72 | hr | 1476 | 1867 | 3694 | 0.5054 | 0.1760 |
| SK-BR-3 | WYE-125132 | 0.37 | uM | LJP6 | 3 | L10 | 72 | hr | 1476 | 1653 | 3694 | 0.4475 | 0.0795 |
| SK-BR-3 | WZ3105 | 0.37 | uM | LJP5 | 1 | D22 | 72 | hr | 1476 | 926 | 3694 | 0.2507 | -0.2484 |
| SK-BR-3 | WZ3105 | 0.37 | uM | LJP5 | 2 | D22 | 72 | hr | 1476 | 1280 | 3694 | 0.3465 | -0.0887 |
| SK-BR-3 | WZ3105 | 0.37 | uM | LJP5 | 3 | D22 | 72 | hr | 1476 | 1340 | 3694 | 0.3628 | -0.0617 |
| SK-BR-3 | XMD11-50 | 0.37 | uM | LJP6 | 1 | P10 | 72 | hr | 1476 | 2710 | 3694 | 0.7336 | 0.5562 |
| SK-BR-3 | XMD11-50 | 0.37 | uM | LJP6 | 2 | P10 | 72 | hr | 1476 | 2539 | 3694 | 0.6873 | 0.4791 |