LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
SK-BR-3 Seliciclib
0.04
uM
LJP5
 3
J06
 72
hr
 1476 4024 3694 1.0893 1.1488
SK-BR-3 Ruxolitinib
0.04
uM
LJP5
 1
O18
 72
hr
 1476 3003 3694 0.8129 0.6883
SK-BR-3 Ruxolitinib
0.04
uM
LJP5
 2
O18
 72
hr
 1476 3356 3694 0.9085 0.8475
SK-BR-3 Ruxolitinib
0.04
uM
LJP5
 3
O18
 72
hr
 1476 3181 3694 0.8611 0.7686
SK-BR-3 XL147
0.04
uM
LJP5
 1
G12
 72
hr
 1476 3992 3694 1.0807 1.1344
SK-BR-3 XL147
0.04
uM
LJP5
 2
G12
 72
hr
 1476 4302 3694 1.1646 1.2742
SK-BR-3 XL147
0.04
uM
LJP5
 3
G12
 72
hr
 1476 4398 3694 1.1906 1.3175
SK-BR-3 Saracatinib
0.04
uM
LJP6
 1
D12
 72
hr
 1476 4380 3694 1.1857 1.3094
SK-BR-3 Saracatinib
0.04
uM
LJP6
 2
D12
 72
hr
 1476 4019 3694 1.0880 1.1465
SK-BR-3 Saracatinib
0.04
uM
LJP6
 3
D12
 72
hr
 1476 4300 3694 1.1640 1.2733
SK-BR-3 Selumetinib
0.04
uM
LJP6
 1
M12
 72
hr
 1476 3894 3694 1.0541 1.0902
SK-BR-3 Selumetinib
0.04
uM
LJP6
 2
M12
 72
hr
 1476 4148 3694 1.1229 1.2047
SK-BR-3 Selumetinib
0.04
uM
LJP6
 3
M12
 72
hr
 1476 3860 3694 1.0449 1.0748
SK-BR-3 Sirolimus
0.04
uM
LJP6
 1
L18
 72
hr
 1476 2090 3694 0.5658 0.2766
SK-BR-3 Sirolimus
0.04
uM
LJP6
 2
L18
 72
hr
 1476 2657 3694 0.7193 0.5323
SK-BR-3 Sirolimus
0.04
uM
LJP6
 3
L18
 72
hr
 1476 2652 3694 0.7179 0.5300
SK-BR-3 Sorafenib
0.04
uM
LJP6
 1
B12
 72
hr
 1476 3399 3694 0.9201 0.8669
SK-BR-3 Sorafenib
0.04
uM
LJP6
 2
B12
 72
hr
 1476 3344 3694 0.9052 0.8421
SK-BR-3 Sorafenib
0.04
uM
LJP6
 3
B12
 72
hr
 1476 3177 3694 0.8600 0.7668
SK-BR-3 SU11274
0.04
uM
LJP5
 1
J12
 72
hr
 1476 4513 3694 1.2217 1.3693
SK-BR-3 SU11274
0.04
uM
LJP5
 2
J12
 72
hr
 1476 4212 3694 1.1402 1.2336
SK-BR-3 SU11274
0.04
uM
LJP5
 3
J12
 72
hr
 1476 4287 3694 1.1605 1.2674
SK-BR-3 Fedratinib
0.04
uM
LJP5
 1
L06
 72
hr
 1476 4034 3694 1.0920 1.1533
SK-BR-3 Fedratinib
0.04
uM
LJP5
 2
L06
 72
hr
 1476 4308 3694 1.1662 1.2769
SK-BR-3 Fedratinib
0.04
uM
LJP5
 3
L06
 72
hr
 1476 4137 3694 1.1199 1.1998