LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | PIK-93 | 0.04 | uM | LJP5 | 3 | K18 | 72 | hr | 1476 | 4295 | 3694 | 1.1627 | 1.2710 |
| SK-BR-3 | KIN001-043 | 0.04 | uM | LJP6 | 1 | C12 | 72 | hr | 1476 | 3370 | 3694 | 0.9123 | 0.8539 |
| SK-BR-3 | KIN001-043 | 0.04 | uM | LJP6 | 2 | C12 | 72 | hr | 1476 | 3761 | 3694 | 1.0181 | 1.0302 |
| SK-BR-3 | KIN001-043 | 0.04 | uM | LJP6 | 3 | C12 | 72 | hr | 1476 | 3989 | 3694 | 1.0798 | 1.1330 |
| SK-BR-3 | Alpelisib | 0.04 | uM | LJP5 | 1 | N06 | 72 | hr | 1476 | 3589 | 3694 | 0.9716 | 0.9526 |
| SK-BR-3 | Alpelisib | 0.04 | uM | LJP5 | 2 | N06 | 72 | hr | 1476 | 3254 | 3694 | 0.8809 | 0.8015 |
| SK-BR-3 | Alpelisib | 0.04 | uM | LJP5 | 3 | N06 | 72 | hr | 1476 | 3391 | 3694 | 0.9180 | 0.8633 |
| SK-BR-3 | Luminespib | 0.04 | uM | LJP5 | 1 | H18 | 72 | hr | 1476 | 1678 | 3694 | 0.4542 | 0.0908 |
| SK-BR-3 | Luminespib | 0.04 | uM | LJP5 | 2 | H18 | 72 | hr | 1476 | 1604 | 3694 | 0.4342 | 0.0574 |
| SK-BR-3 | Luminespib | 0.04 | uM | LJP5 | 3 | H18 | 72 | hr | 1476 | 1573 | 3694 | 0.4258 | 0.0434 |
| SK-BR-3 | A443654 | 0.04 | uM | LJP6 | 1 | I24 | 72 | hr | 1476 | 1101 | 3694 | 0.2981 | -0.1695 |
| SK-BR-3 | A443654 | 0.04 | uM | LJP6 | 2 | I24 | 72 | hr | 1476 | 1196 | 3694 | 0.3238 | -0.1266 |
| SK-BR-3 | A443654 | 0.04 | uM | LJP6 | 3 | I24 | 72 | hr | 1476 | 1223 | 3694 | 0.3311 | -0.1144 |
| SK-BR-3 | OSI-027 | 0.04 | uM | LJP6 | 1 | E12 | 72 | hr | 1476 | 2853 | 3694 | 0.7723 | 0.6207 |
| SK-BR-3 | OSI-027 | 0.04 | uM | LJP6 | 2 | E12 | 72 | hr | 1476 | 3433 | 3694 | 0.9293 | 0.8823 |
| SK-BR-3 | OSI-027 | 0.04 | uM | LJP6 | 3 | E12 | 72 | hr | 1476 | 3536 | 3694 | 0.9572 | 0.9287 |
| SK-BR-3 | XMD11-85h | 0.04 | uM | LJP6 | 1 | P24 | 72 | hr | 1476 | 2849 | 3694 | 0.7712 | 0.6189 |
| SK-BR-3 | XMD11-85h | 0.04 | uM | LJP6 | 2 | P24 | 72 | hr | 1476 | 2542 | 3694 | 0.6881 | 0.4804 |
| SK-BR-3 | XMD11-85h | 0.04 | uM | LJP6 | 3 | P24 | 72 | hr | 1476 | 2494 | 3694 | 0.6751 | 0.4588 |
| SK-BR-3 | HG-6-64-01 | 0.04 | uM | LJP6 | 1 | M06 | 72 | hr | 1476 | 4124 | 3694 | 1.1164 | 1.1939 |
| SK-BR-3 | HG-6-64-01 | 0.04 | uM | LJP6 | 2 | M06 | 72 | hr | 1476 | 4473 | 3694 | 1.2109 | 1.3513 |
| SK-BR-3 | HG-6-64-01 | 0.04 | uM | LJP6 | 3 | M06 | 72 | hr | 1476 | 3757 | 3694 | 1.0170 | 1.0284 |
| SK-BR-3 | WH-4-025 | 0.04 | uM | LJP5 | 1 | O12 | 72 | hr | 1476 | 4304 | 3694 | 1.1651 | 1.2751 |
| SK-BR-3 | WH-4-025 | 0.04 | uM | LJP5 | 2 | O12 | 72 | hr | 1476 | 3617 | 3694 | 0.9791 | 0.9653 |
| SK-BR-3 | WH-4-025 | 0.04 | uM | LJP5 | 3 | O12 | 72 | hr | 1476 | 3607 | 3694 | 0.9764 | 0.9607 |