LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 Dasatinib
10.0
uM
LJP6
 1
I01
 72
hr
 868 397 3486 0.1139 -0.1799
MDA-MB-231 Dasatinib
10.0
uM
LJP6
 2
I01
 72
hr
 868 445 3486 0.1276 -0.1616
MDA-MB-231 Dasatinib
10.0
uM
LJP6
 3
I01
 72
hr
 868 526 3486 0.1509 -0.1307
MDA-MB-231 Dovitinib
10.0
uM
LJP5
 1
E19
 72
hr
 868 1557 3486 0.4466 0.2631
MDA-MB-231 Dovitinib
10.0
uM
LJP5
 2
E19
 72
hr
 868 1412 3486 0.4050 0.2077
MDA-MB-231 Dovitinib
10.0
uM
LJP5
 3
E19
 72
hr
 868 1515 3486 0.4346 0.2471
MDA-MB-231 Enzastaurin
10.0
uM
LJP5
 1
D13
 72
hr
 868 3224 3486 0.9247 0.8998
MDA-MB-231 Enzastaurin
10.0
uM
LJP5
 2
D13
 72
hr
 868 3329 3486 0.9549 0.9399
MDA-MB-231 Enzastaurin
10.0
uM
LJP5
 3
D13
 72
hr
 868 3238 3486 0.9288 0.9051
MDA-MB-231 Erlotinib
10.0
uM
LJP5
 1
M19
 72
hr
 868 2014 3486 0.5777 0.4377
MDA-MB-231 Erlotinib
10.0
uM
LJP5
 2
M19
 72
hr
 868 2315 3486 0.6640 0.5526
MDA-MB-231 Erlotinib
10.0
uM
LJP5
 3
M19
 72
hr
 868 1995 3486 0.5722 0.4304
MDA-MB-231 Foretinib
10.0
uM
LJP5
 1
H07
 72
hr
 868 654 3486 0.1876 -0.0818
MDA-MB-231 Foretinib
10.0
uM
LJP5
 2
H07
 72
hr
 868 687 3486 0.1971 -0.0692
MDA-MB-231 Foretinib
10.0
uM
LJP5
 3
H07
 72
hr
 868 565 3486 0.1621 -0.1158
MDA-MB-231 R406
10.0
uM
LJP6
 1
C13
 72
hr
 868 1789 3486 0.5131 0.3517
MDA-MB-231 R406
10.0
uM
LJP6
 2
C13
 72
hr
 868 1532 3486 0.4394 0.2536
MDA-MB-231 R406
10.0
uM
LJP6
 3
C13
 72
hr
 868 1756 3486 0.5037 0.3391
MDA-MB-231 Pictilisib
10.0
uM
LJP6
 1
D19
 72
hr
 868 1884 3486 0.5404 0.3880
MDA-MB-231 Pictilisib
10.0
uM
LJP6
 2
D19
 72
hr
 868 1727 3486 0.4954 0.3280
MDA-MB-231 Pictilisib
10.0
uM
LJP6
 3
D19
 72
hr
 868 1808 3486 0.5186 0.3590
MDA-MB-231 Gefitinib
10.0
uM
LJP6
 1
N07
 72
hr
 868 3036 3486 0.8708 0.8280
MDA-MB-231 Gefitinib
10.0
uM
LJP6
 2
N07
 72
hr
 868 3294 3486 0.9448 0.9265
MDA-MB-231 Gefitinib
10.0
uM
LJP6
 3
N07
 72
hr
 868 3123 3486 0.8958 0.8612
MDA-MB-231 Geldanamycin
10.0
uM
LJP5
 1
O01
 72
hr
 868 638 3486 0.1830 -0.0879