LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 TWS119
3.33
uM
LJP5
 1
M02
 72
hr
 868 1884 3486 0.5404 0.3880
MDA-MB-231 TWS119
3.33
uM
LJP5
 2
M02
 72
hr
 868 2134 3486 0.6121 0.4835
MDA-MB-231 TWS119
3.33
uM
LJP5
 3
M02
 72
hr
 868 2773 3486 0.7954 0.7275
MDA-MB-231 Vemurafenib
3.33
uM
LJP5
 1
C14
 72
hr
 868 2758 3486 0.7911 0.7218
MDA-MB-231 Vemurafenib
3.33
uM
LJP5
 2
C14
 72
hr
 868 2803 3486 0.8040 0.7390
MDA-MB-231 Vemurafenib
3.33
uM
LJP5
 3
C14
 72
hr
 868 2727 3486 0.7822 0.7100
MDA-MB-231 Withaferin A
3.33
uM
LJP5
 1
G14
 72
hr
 868 921 3486 0.2642 0.0202
MDA-MB-231 Withaferin A
3.33
uM
LJP5
 2
G14
 72
hr
 868 816 3486 0.2341 -0.0199
MDA-MB-231 Withaferin A
3.33
uM
LJP5
 3
G14
 72
hr
 868 568 3486 0.1629 -0.1146
MDA-MB-231 Withaferin A
3.33
uM
LJP6
 1
G14
 72
hr
 868 663 3486 0.1902 -0.0783
MDA-MB-231 Withaferin A
3.33
uM
LJP6
 2
G14
 72
hr
 868 793 3486 0.2275 -0.0287
MDA-MB-231 Withaferin A
3.33
uM
LJP6
 3
G14
 72
hr
 868 571 3486 0.1638 -0.1135
MDA-MB-231 WYE-125132
3.33
uM
LJP6
 1
L08
 72
hr
 868 1527 3486 0.4380 0.2517
MDA-MB-231 WYE-125132
3.33
uM
LJP6
 2
L08
 72
hr
 868 1728 3486 0.4956 0.3284
MDA-MB-231 WYE-125132
3.33
uM
LJP6
 3
L08
 72
hr
 868 1597 3486 0.4581 0.2784
MDA-MB-231 WZ3105
3.33
uM
LJP5
 1
D20
 72
hr
 868 584 3486 0.1675 -0.1085
MDA-MB-231 WZ3105
3.33
uM
LJP5
 2
D20
 72
hr
 868 714 3486 0.2048 -0.0589
MDA-MB-231 WZ3105
3.33
uM
LJP5
 3
D20
 72
hr
 868 748 3486 0.2146 -0.0459
MDA-MB-231 XMD11-50
3.33
uM
LJP6
 1
P08
 72
hr
 868 1072 3486 0.3075 0.0779
MDA-MB-231 XMD11-50
3.33
uM
LJP6
 2
P08
 72
hr
 868 1362 3486 0.3907 0.1886
MDA-MB-231 XMD11-50
3.33
uM
LJP6
 3
P08
 72
hr
 868 1322 3486 0.3792 0.1734
MDA-MB-231 Y39983
3.33
uM
LJP6
 1
P02
 72
hr
 868 1823 3486 0.5229 0.3647
MDA-MB-231 Y39983
3.33
uM
LJP6
 2
P02
 72
hr
 868 2362 3486 0.6775 0.5706
MDA-MB-231 Y39983
3.33
uM
LJP6
 3
P02
 72
hr
 868 2039 3486 0.5848 0.4472
MDA-MB-231 YM 201636
3.33
uM
LJP5
 1
N08
 72
hr
 868 2682 3486 0.7693 0.6928