LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 GDC-0980
3.33
uM
LJP5
 2
K20
 72
hr
 868 1624 3486 0.4658 0.2887
MDA-MB-231 GDC-0980
3.33
uM
LJP5
 3
K20
 72
hr
 868 1558 3486 0.4469 0.2635
MDA-MB-231 NVP-AEW541
3.33
uM
LJP5
 1
E14
 72
hr
 868 3413 3486 0.9790 0.9720
MDA-MB-231 NVP-AEW541
3.33
uM
LJP5
 2
E14
 72
hr
 868 3340 3486 0.9580 0.9441
MDA-MB-231 NVP-AEW541
3.33
uM
LJP5
 3
E14
 72
hr
 868 3387 3486 0.9715 0.9620
MDA-MB-231 SB590885
3.33
uM
LJP5
 1
L14
 72
hr
 868 1863 3486 0.5344 0.3800
MDA-MB-231 SB590885
3.33
uM
LJP5
 2
L14
 72
hr
 868 2055 3486 0.5894 0.4533
MDA-MB-231 SB590885
3.33
uM
LJP5
 3
L14
 72
hr
 868 1843 3486 0.5286 0.3723
MDA-MB-231 PIK-93
3.33
uM
LJP5
 1
K14
 72
hr
 868 2330 3486 0.6683 0.5583
MDA-MB-231 PIK-93
3.33
uM
LJP5
 2
K14
 72
hr
 868 2864 3486 0.8215 0.7623
MDA-MB-231 PIK-93
3.33
uM
LJP5
 3
K14
 72
hr
 868 2612 3486 0.7492 0.6660
MDA-MB-231 KIN001-043
3.33
uM
LJP6
 1
C08
 72
hr
 868 3388 3486 0.9718 0.9624
MDA-MB-231 KIN001-043
3.33
uM
LJP6
 2
C08
 72
hr
 868 3482 3486 0.9987 0.9983
MDA-MB-231 KIN001-043
3.33
uM
LJP6
 3
C08
 72
hr
 868 3169 3486 0.9090 0.8788
MDA-MB-231 Alpelisib
3.33
uM
LJP5
 1
N02
 72
hr
 868 2906 3486 0.8335 0.7783
MDA-MB-231 Alpelisib
3.33
uM
LJP5
 2
N02
 72
hr
 868 3082 3486 0.8840 0.8456
MDA-MB-231 Alpelisib
3.33
uM
LJP5
 3
N02
 72
hr
 868 3013 3486 0.8642 0.8192
MDA-MB-231 Luminespib
3.33
uM
LJP5
 1
H14
 72
hr
 868 979 3486 0.2808 0.0423
MDA-MB-231 Luminespib
3.33
uM
LJP5
 2
H14
 72
hr
 868 1005 3486 0.2883 0.0523
MDA-MB-231 Luminespib
3.33
uM
LJP5
 3
H14
 72
hr
 868 1038 3486 0.2977 0.0649
MDA-MB-231 A443654
3.33
uM
LJP6
 1
I20
 72
hr
 868 506 3486 0.1451 -0.1383
MDA-MB-231 A443654
3.33
uM
LJP6
 2
I20
 72
hr
 868 514 3486 0.1474 -0.1353
MDA-MB-231 A443654
3.33
uM
LJP6
 3
I20
 72
hr
 868 696 3486 0.1996 -0.0657
MDA-MB-231 OSI-027
3.33
uM
LJP6
 1
E08
 72
hr
 868 2277 3486 0.6531 0.5381
MDA-MB-231 OSI-027
3.33
uM
LJP6
 2
E08
 72
hr
 868 2380 3486 0.6827 0.5774