LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 XMD11-50
1.11
uM
LJP6
 3
P09
 72
hr
 868 1432 3486 0.4107 0.2154
MDA-MB-231 Y39983
1.11
uM
LJP6
 1
P03
 72
hr
 868 2286 3486 0.6557 0.5415
MDA-MB-231 Y39983
1.11
uM
LJP6
 2
P03
 72
hr
 868 2686 3486 0.7704 0.6943
MDA-MB-231 Y39983
1.11
uM
LJP6
 3
P03
 72
hr
 868 2686 3486 0.7704 0.6943
MDA-MB-231 YM 201636
1.11
uM
LJP5
 1
N09
 72
hr
 868 2699 3486 0.7742 0.6993
MDA-MB-231 YM 201636
1.11
uM
LJP5
 2
N09
 72
hr
 868 3029 3486 0.8688 0.8253
MDA-MB-231 YM 201636
1.11
uM
LJP5
 3
N09
 72
hr
 868 2797 3486 0.8023 0.7367
MDA-MB-231 ZSTK474
1.11
uM
LJP6
 1
M15
 72
hr
 868 2445 3486 0.7013 0.6023
MDA-MB-231 ZSTK474
1.11
uM
LJP6
 2
M15
 72
hr
 868 2421 3486 0.6944 0.5931
MDA-MB-231 ZSTK474
1.11
uM
LJP6
 3
M15
 72
hr
 868 2497 3486 0.7162 0.6221
MDA-MB-231 Afatinib
3.33
uM
LJP6
 1
G20
 72
hr
 868 2252 3486 0.6459 0.5286
MDA-MB-231 Afatinib
3.33
uM
LJP6
 2
G20
 72
hr
 868 2069 3486 0.5935 0.4587
MDA-MB-231 Afatinib
3.33
uM
LJP6
 3
G20
 72
hr
 868 2226 3486 0.6385 0.5186
MDA-MB-231 Sigma A6730
3.33
uM
LJP5
 1
B20
 72
hr
 868 2882 3486 0.8266 0.7692
MDA-MB-231 Sigma A6730
3.33
uM
LJP5
 2
B20
 72
hr
 868 2993 3486 0.8585 0.8116
MDA-MB-231 Sigma A6730
3.33
uM
LJP5
 3
B20
 72
hr
 868 3005 3486 0.8619 0.8161
MDA-MB-231 Alvocidib
3.33
uM
LJP6
 1
A14
 72
hr
 868 700 3486 0.2008 -0.0642
MDA-MB-231 Alvocidib
3.33
uM
LJP6
 2
A14
 72
hr
 868 579 3486 0.1661 -0.1104
MDA-MB-231 Alvocidib
3.33
uM
LJP6
 3
A14
 72
hr
 868 557 3486 0.1598 -0.1188
MDA-MB-231 AT-7519
3.33
uM
LJP6
 1
K02
 72
hr
 868 551 3486 0.1580 -0.1211
MDA-MB-231 AT-7519
3.33
uM
LJP6
 2
K02
 72
hr
 868 559 3486 0.1603 -0.1181
MDA-MB-231 AT-7519
3.33
uM
LJP6
 3
K02
 72
hr
 868 656 3486 0.1882 -0.0810
MDA-MB-231 AZD 5438
3.33
uM
LJP6
 1
J02
 72
hr
 868 830 3486 0.2381 -0.0146
MDA-MB-231 AZD 5438
3.33
uM
LJP6
 2
J02
 72
hr
 868 831 3486 0.2384 -0.0142
MDA-MB-231 AZD 5438
3.33
uM
LJP6
 3
J02
 72
hr
 868 720 3486 0.2065 -0.0566