LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 BMS345541
1.11
uM
LJP6
 3
D03
 72
hr
 868 2289 3486 0.6566 0.5427
MDA-MB-231 SNS-032
1.11
uM
LJP6
 1
H15
 72
hr
 868 732 3486 0.2100 -0.0520
MDA-MB-231 SNS-032
1.11
uM
LJP6
 2
H15
 72
hr
 868 760 3486 0.2180 -0.0413
MDA-MB-231 SNS-032
1.11
uM
LJP6
 3
H15
 72
hr
 868 753 3486 0.2160 -0.0440
MDA-MB-231 GDC-0980
1.11
uM
LJP5
 1
K21
 72
hr
 868 1513 3486 0.4340 0.2463
MDA-MB-231 GDC-0980
1.11
uM
LJP5
 2
K21
 72
hr
 868 1626 3486 0.4664 0.2895
MDA-MB-231 GDC-0980
1.11
uM
LJP5
 3
K21
 72
hr
 868 1723 3486 0.4942 0.3265
MDA-MB-231 NVP-AEW541
1.11
uM
LJP5
 1
E15
 72
hr
 868 3544 3486 1.0165 1.0220
MDA-MB-231 NVP-AEW541
1.11
uM
LJP5
 2
E15
 72
hr
 868 3436 3486 0.9855 0.9808
MDA-MB-231 NVP-AEW541
1.11
uM
LJP5
 3
E15
 72
hr
 868 3252 3486 0.9328 0.9105
MDA-MB-231 SB590885
1.11
uM
LJP5
 1
L15
 72
hr
 868 2057 3486 0.5900 0.4541
MDA-MB-231 SB590885
1.11
uM
LJP5
 2
L15
 72
hr
 868 2426 3486 0.6959 0.5950
MDA-MB-231 SB590885
1.11
uM
LJP5
 3
L15
 72
hr
 868 2396 3486 0.6872 0.5835
MDA-MB-231 PIK-93
1.11
uM
LJP5
 1
K15
 72
hr
 868 3182 3486 0.9127 0.8837
MDA-MB-231 PIK-93
1.11
uM
LJP5
 2
K15
 72
hr
 868 3453 3486 0.9904 0.9872
MDA-MB-231 PIK-93
1.11
uM
LJP5
 3
K15
 72
hr
 868 3281 3486 0.9411 0.9216
MDA-MB-231 KIN001-043
1.11
uM
LJP6
 1
C09
 72
hr
 868 2966 3486 0.8507 0.8012
MDA-MB-231 KIN001-043
1.11
uM
LJP6
 2
C09
 72
hr
 868 3086 3486 0.8852 0.8471
MDA-MB-231 KIN001-043
1.11
uM
LJP6
 3
C09
 72
hr
 868 3418 3486 0.9804 0.9739
MDA-MB-231 Alpelisib
1.11
uM
LJP5
 1
N03
 72
hr
 868 3113 3486 0.8929 0.8574
MDA-MB-231 Alpelisib
1.11
uM
LJP5
 2
N03
 72
hr
 868 3292 3486 0.9442 0.9258
MDA-MB-231 Alpelisib
1.11
uM
LJP5
 3
N03
 72
hr
 868 3293 3486 0.9445 0.9261
MDA-MB-231 Luminespib
1.11
uM
LJP5
 1
H15
 72
hr
 868 980 3486 0.2811 0.0427
MDA-MB-231 Luminespib
1.11
uM
LJP5
 2
H15
 72
hr
 868 1028 3486 0.2949 0.0611
MDA-MB-231 Luminespib
1.11
uM
LJP5
 3
H15
 72
hr
 868 1035 3486 0.2969 0.0637