LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 Sigma A6730
0.37
uM
LJP5
 3
B22
 72
hr
 868 2945 3486 0.8447 0.7932
MDA-MB-231 Alvocidib
0.37
uM
LJP6
 1
A16
 72
hr
 868 620 3486 0.1778 -0.0948
MDA-MB-231 Alvocidib
0.37
uM
LJP6
 2
A16
 72
hr
 868 597 3486 0.1712 -0.1036
MDA-MB-231 Alvocidib
0.37
uM
LJP6
 3
A16
 72
hr
 868 616 3486 0.1767 -0.0963
MDA-MB-231 AT-7519
0.37
uM
LJP6
 1
K04
 72
hr
 868 1033 3486 0.2963 0.0630
MDA-MB-231 AT-7519
0.37
uM
LJP6
 2
K04
 72
hr
 868 949 3486 0.2722 0.0309
MDA-MB-231 AT-7519
0.37
uM
LJP6
 3
K04
 72
hr
 868 913 3486 0.2619 0.0171
MDA-MB-231 AZD 5438
0.37
uM
LJP6
 1
J04
 72
hr
 868 1590 3486 0.4561 0.2757
MDA-MB-231 AZD 5438
0.37
uM
LJP6
 2
J04
 72
hr
 868 1762 3486 0.5054 0.3414
MDA-MB-231 AZD 5438
0.37
uM
LJP6
 3
J04
 72
hr
 868 1602 3486 0.4595 0.2803
MDA-MB-231 AZD-6482
0.37
uM
LJP5
 1
I04
 72
hr
 868 2986 3486 0.8565 0.8089
MDA-MB-231 AZD-6482
0.37
uM
LJP5
 2
I04
 72
hr
 868 3179 3486 0.9118 0.8826
MDA-MB-231 AZD-6482
0.37
uM
LJP5
 3
I04
 72
hr
 868 2916 3486 0.8364 0.7822
MDA-MB-231 AZD7762
0.37
uM
LJP6
 1
L04
 72
hr
 868 1316 3486 0.3775 0.1711
MDA-MB-231 AZD7762
0.37
uM
LJP6
 2
L04
 72
hr
 868 1435 3486 0.4116 0.2165
MDA-MB-231 AZD7762
0.37
uM
LJP6
 3
L04
 72
hr
 868 1303 3486 0.3737 0.1661
MDA-MB-231 AZD8055
0.37
uM
LJP6
 1
A10
 72
hr
 868 1627 3486 0.4667 0.2898
MDA-MB-231 AZD8055
0.37
uM
LJP6
 2
A10
 72
hr
 868 1357 3486 0.3892 0.1867
MDA-MB-231 AZD8055
0.37
uM
LJP6
 3
A10
 72
hr
 868 1111 3486 0.3187 0.0928
MDA-MB-231 AZD8330
0.37
uM
LJP5
 1
G22
 72
hr
 868 849 3486 0.2435 -0.0073
MDA-MB-231 AZD8330
0.37
uM
LJP5
 2
G22
 72
hr
 868 934 3486 0.2679 0.0252
MDA-MB-231 AZD8330
0.37
uM
LJP5
 3
G22
 72
hr
 868 975 3486 0.2797 0.0408
MDA-MB-231 Barasertib
0.37
uM
LJP5
 1
D10
 72
hr
 868 1268 3486 0.3637 0.1527
MDA-MB-231 Barasertib
0.37
uM
LJP5
 2
D10
 72
hr
 868 1202 3486 0.3448 0.1275
MDA-MB-231 Barasertib
0.37
uM
LJP5
 3
D10
 72
hr
 868 1264 3486 0.3626 0.1512