LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 Dovitinib
0.12
uM
LJP5
 3
E23
 72
hr
 868 2417 3486 0.6933 0.5916
MDA-MB-231 Enzastaurin
0.12
uM
LJP5
 1
D17
 72
hr
 868 3287 3486 0.9428 0.9238
MDA-MB-231 Enzastaurin
0.12
uM
LJP5
 2
D17
 72
hr
 868 3270 3486 0.9379 0.9174
MDA-MB-231 Enzastaurin
0.12
uM
LJP5
 3
D17
 72
hr
 868 3700 3486 1.0613 1.0816
MDA-MB-231 Erlotinib
0.12
uM
LJP5
 1
M23
 72
hr
 868 3218 3486 0.9230 0.8975
MDA-MB-231 Erlotinib
0.12
uM
LJP5
 2
M23
 72
hr
 868 3145 3486 0.9021 0.8696
MDA-MB-231 Erlotinib
0.12
uM
LJP5
 3
M23
 72
hr
 868 3160 3486 0.9064 0.8753
MDA-MB-231 Foretinib
0.12
uM
LJP5
 1
H11
 72
hr
 868 2289 3486 0.6566 0.5427
MDA-MB-231 Foretinib
0.12
uM
LJP5
 2
H11
 72
hr
 868 2305 3486 0.6611 0.5488
MDA-MB-231 Foretinib
0.12
uM
LJP5
 3
H11
 72
hr
 868 2216 3486 0.6356 0.5148
MDA-MB-231 R406
0.12
uM
LJP6
 1
C17
 72
hr
 868 3279 3486 0.9405 0.9208
MDA-MB-231 R406
0.12
uM
LJP6
 2
C17
 72
hr
 868 3141 3486 0.9009 0.8681
MDA-MB-231 R406
0.12
uM
LJP6
 3
C17
 72
hr
 868 3186 3486 0.9138 0.8853
MDA-MB-231 Pictilisib
0.12
uM
LJP6
 1
D23
 72
hr
 868 2563 3486 0.7351 0.6473
MDA-MB-231 Pictilisib
0.12
uM
LJP6
 2
D23
 72
hr
 868 2710 3486 0.7773 0.7035
MDA-MB-231 Pictilisib
0.12
uM
LJP6
 3
D23
 72
hr
 868 2562 3486 0.7349 0.6469
MDA-MB-231 Gefitinib
0.12
uM
LJP6
 1
N11
 72
hr
 868 3634 3486 1.0423 1.0564
MDA-MB-231 Gefitinib
0.12
uM
LJP6
 2
N11
 72
hr
 868 4003 3486 1.1482 1.1973
MDA-MB-231 Gefitinib
0.12
uM
LJP6
 3
N11
 72
hr
 868 4165 3486 1.1946 1.2592
MDA-MB-231 Geldanamycin
0.12
uM
LJP5
 1
O05
 72
hr
 868 1065 3486 0.3055 0.0752
MDA-MB-231 Geldanamycin
0.12
uM
LJP5
 2
O05
 72
hr
 868 1053 3486 0.3020 0.0706
MDA-MB-231 Geldanamycin
0.12
uM
LJP5
 3
O05
 72
hr
 868 1127 3486 0.3233 0.0989
MDA-MB-231 Geldanamycin
0.12
uM
LJP6
 1
O05
 72
hr
 868 1152 3486 0.3304 0.1084
MDA-MB-231 Geldanamycin
0.12
uM
LJP6
 2
O05
 72
hr
 868 1259 3486 0.3611 0.1493
MDA-MB-231 Geldanamycin
0.12
uM
LJP6
 3
O05
 72
hr
 868 1270 3486 0.3643 0.1535