LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 AZD8330
0.12
uM
LJP5
 2
G23
 72
hr
 868 967 3486 0.2774 0.0378
MDA-MB-231 AZD8330
0.12
uM
LJP5
 3
G23
 72
hr
 868 904 3486 0.2593 0.0137
MDA-MB-231 Barasertib
0.12
uM
LJP5
 1
D11
 72
hr
 868 1355 3486 0.3887 0.1860
MDA-MB-231 Barasertib
0.12
uM
LJP5
 2
D11
 72
hr
 868 1187 3486 0.3405 0.1218
MDA-MB-231 Barasertib
0.12
uM
LJP5
 3
D11
 72
hr
 868 1295 3486 0.3714 0.1630
MDA-MB-231 BI-2536
0.12
uM
LJP6
 1
D17
 72
hr
 868 1200 3486 0.3442 0.1268
MDA-MB-231 BI-2536
0.12
uM
LJP6
 2
D17
 72
hr
 868 1021 3486 0.2929 0.0584
MDA-MB-231 BI-2536
0.12
uM
LJP6
 3
D17
 72
hr
 868 1078 3486 0.3092 0.0802
MDA-MB-231 BMS345541
0.12
uM
LJP6
 1
D05
 72
hr
 868 4085 3486 1.1717 1.2286
MDA-MB-231 BMS345541
0.12
uM
LJP6
 2
D05
 72
hr
 868 3550 3486 1.0182 1.0243
MDA-MB-231 BMS345541
0.12
uM
LJP6
 3
D05
 72
hr
 868 3366 3486 0.9655 0.9540
MDA-MB-231 SNS-032
0.12
uM
LJP6
 1
H17
 72
hr
 868 800 3486 0.2295 -0.0260
MDA-MB-231 SNS-032
0.12
uM
LJP6
 2
H17
 72
hr
 868 846 3486 0.2427 -0.0084
MDA-MB-231 SNS-032
0.12
uM
LJP6
 3
H17
 72
hr
 868 817 3486 0.2343 -0.0195
MDA-MB-231 GDC-0980
0.12
uM
LJP5
 1
K23
 72
hr
 868 2067 3486 0.5929 0.4579
MDA-MB-231 GDC-0980
0.12
uM
LJP5
 2
K23
 72
hr
 868 2371 3486 0.6801 0.5740
MDA-MB-231 GDC-0980
0.12
uM
LJP5
 3
K23
 72
hr
 868 2222 3486 0.6373 0.5171
MDA-MB-231 NVP-AEW541
0.12
uM
LJP5
 1
E17
 72
hr
 868 3555 3486 1.0197 1.0262
MDA-MB-231 NVP-AEW541
0.12
uM
LJP5
 2
E17
 72
hr
 868 3305 3486 0.9480 0.9307
MDA-MB-231 NVP-AEW541
0.12
uM
LJP5
 3
E17
 72
hr
 868 3651 3486 1.0472 1.0629
MDA-MB-231 SB590885
0.12
uM
LJP5
 1
L17
 72
hr
 868 3052 3486 0.8754 0.8341
MDA-MB-231 SB590885
0.12
uM
LJP5
 2
L17
 72
hr
 868 3622 3486 1.0389 1.0518
MDA-MB-231 SB590885
0.12
uM
LJP5
 3
L17
 72
hr
 868 3135 3486 0.8992 0.8658
MDA-MB-231 PIK-93
0.12
uM
LJP5
 1
K17
 72
hr
 868 3268 3486 0.9374 0.9166
MDA-MB-231 PIK-93
0.12
uM
LJP5
 2
K17
 72
hr
 868 4066 3486 1.1662 1.2214