LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 Vemurafenib
0.04
uM
LJP5
 3
C18
 72
hr
 868 3544 3486 1.0165 1.0220
MDA-MB-231 Withaferin A
0.04
uM
LJP5
 1
G18
 72
hr
 868 3901 3486 1.1189 1.1583
MDA-MB-231 Withaferin A
0.04
uM
LJP5
 2
G18
 72
hr
 868 3636 3486 1.0429 1.0571
MDA-MB-231 Withaferin A
0.04
uM
LJP5
 3
G18
 72
hr
 868 4089 3486 1.1728 1.2302
MDA-MB-231 Withaferin A
0.04
uM
LJP6
 1
G18
 72
hr
 868 3714 3486 1.0653 1.0869
MDA-MB-231 Withaferin A
0.04
uM
LJP6
 2
G18
 72
hr
 868 3424 3486 0.9821 0.9762
MDA-MB-231 Withaferin A
0.04
uM
LJP6
 3
G18
 72
hr
 868 3684 3486 1.0567 1.0755
MDA-MB-231 WYE-125132
0.04
uM
LJP6
 1
L12
 72
hr
 868 2300 3486 0.6597 0.5469
MDA-MB-231 WYE-125132
0.04
uM
LJP6
 2
L12
 72
hr
 868 2205 3486 0.6325 0.5106
MDA-MB-231 WYE-125132
0.04
uM
LJP6
 3
L12
 72
hr
 868 2316 3486 0.6643 0.5530
MDA-MB-231 WZ3105
0.04
uM
LJP5
 1
D24
 72
hr
 868 583 3486 0.1672 -0.1089
MDA-MB-231 WZ3105
0.04
uM
LJP5
 2
D24
 72
hr
 868 792 3486 0.2272 -0.0291
MDA-MB-231 WZ3105
0.04
uM
LJP5
 3
D24
 72
hr
 868 672 3486 0.1928 -0.0749
MDA-MB-231 XMD11-50
0.04
uM
LJP6
 1
P12
 72
hr
 868 2601 3486 0.7460 0.6618
MDA-MB-231 XMD11-50
0.04
uM
LJP6
 2
P12
 72
hr
 868 3303 3486 0.9474 0.9300
MDA-MB-231 XMD11-50
0.04
uM
LJP6
 3
P12
 72
hr
 868 3329 3486 0.9549 0.9399
MDA-MB-231 Y39983
0.04
uM
LJP6
 1
P06
 72
hr
 868 2642 3486 0.7578 0.6775
MDA-MB-231 Y39983
0.04
uM
LJP6
 2
P06
 72
hr
 868 3518 3486 1.0091 1.0121
MDA-MB-231 Y39983
0.04
uM
LJP6
 3
P06
 72
hr
 868 3554 3486 1.0194 1.0258
MDA-MB-231 YM 201636
0.04
uM
LJP5
 1
N12
 72
hr
 868 3401 3486 0.9755 0.9674
MDA-MB-231 YM 201636
0.04
uM
LJP5
 2
N12
 72
hr
 868 4088 3486 1.1726 1.2298
MDA-MB-231 YM 201636
0.04
uM
LJP5
 3
N12
 72
hr
 868 3330 3486 0.9551 0.9403
MDA-MB-231 ZSTK474
0.04
uM
LJP6
 1
M18
 72
hr
 868 3172 3486 0.9098 0.8799
MDA-MB-231 ZSTK474
0.04
uM
LJP6
 2
M18
 72
hr
 868 3592 3486 1.0303 1.0403
MDA-MB-231 ZSTK474
0.04
uM
LJP6
 3
M18
 72
hr
 868 3250 3486 0.9322 0.9097