LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Omipalisib | 10.0 | uM | LJP6 | 2 | N01 | 72 | hr | 1476 | 733 | 3694 | 0.1984 | -0.3354 |
| SK-BR-3 | LDN-193189 | 10.0 | uM | LJP5 | 2 | G01 | 72 | hr | 1476 | 741 | 3694 | 0.2006 | -0.3318 |
| SK-BR-3 | QL-XII-47 | 10.0 | uM | LJP6 | 3 | O19 | 72 | hr | 1476 | 748 | 3694 | 0.2025 | -0.3287 |
| SK-BR-3 | SNS-032 | 10.0 | uM | LJP6 | 3 | H13 | 72 | hr | 1476 | 752 | 3694 | 0.2036 | -0.3268 |
| SK-BR-3 | SNS-032 | 0.37 | uM | LJP6 | 1 | H16 | 72 | hr | 1476 | 757 | 3694 | 0.2049 | -0.3246 |
| SK-BR-3 | CGP60474 | 10.0 | uM | LJP6 | 1 | G01 | 72 | hr | 1476 | 762 | 3694 | 0.2063 | -0.3223 |
| SK-BR-3 | Withaferin A | 3.33 | uM | LJP6 | 3 | G14 | 72 | hr | 1476 | 762 | 3694 | 0.2063 | -0.3223 |
| SK-BR-3 | Geldanamycin | 10.0 | uM | LJP6 | 2 | O01 | 72 | hr | 1476 | 763 | 3694 | 0.2066 | -0.3219 |
| SK-BR-3 | GSK1059615 | 10.0 | uM | LJP6 | 3 | C01 | 72 | hr | 1476 | 765 | 3694 | 0.2071 | -0.3210 |
| SK-BR-3 | CGP60474 | 3.33 | uM | LJP6 | 1 | G02 | 72 | hr | 1476 | 769 | 3694 | 0.2082 | -0.3192 |
| SK-BR-3 | SNS-032 | 10.0 | uM | LJP6 | 1 | H13 | 72 | hr | 1476 | 779 | 3694 | 0.2109 | -0.3147 |
| SK-BR-3 | CGP60474 | 0.12 | uM | LJP6 | 3 | G05 | 72 | hr | 1476 | 780 | 3694 | 0.2112 | -0.3142 |
| MCF7 | AZD 5438 | 10.0 | uM | LJP6 | 2 | J01 | 72 | hr | 1235 | 319 | 4156 | 0.0768 | -0.3138 |
| SK-BR-3 | Withaferin A | 3.33 | uM | LJP5 | 3 | G14 | 72 | hr | 1476 | 783 | 3694 | 0.2120 | -0.3129 |
| SK-BR-3 | CGP60474 | 3.33 | uM | LJP6 | 3 | G02 | 72 | hr | 1476 | 784 | 3694 | 0.2122 | -0.3124 |
| SK-BR-3 | AZD 5438 | 10.0 | uM | LJP6 | 3 | J01 | 72 | hr | 1476 | 787 | 3694 | 0.2131 | -0.3111 |
| BT-20 | LDN-193189 | 10.0 | uM | LJP5 | 1 | G01 | 72 | hr | 1657 | 463 | 5505 | 0.0841 | -0.3105 |
| MCF7 | Alvocidib | 10.0 | uM | LJP6 | 1 | A13 | 72 | hr | 1235 | 329 | 4156 | 0.0792 | -0.3103 |
| SK-BR-3 | AZD7762 | 1.11 | uM | LJP6 | 1 | L03 | 72 | hr | 1476 | 791 | 3694 | 0.2141 | -0.3093 |
| MCF7 | Mitoxantrone | 10.0 | uM | LJP5 | 3 | C19 | 72 | hr | 1235 | 332 | 4156 | 0.0799 | -0.3093 |
| SK-BR-3 | Alvocidib | 1.11 | uM | LJP6 | 3 | A15 | 72 | hr | 1476 | 794 | 3694 | 0.2149 | -0.3079 |
| SK-BR-3 | JW-7-24-1 | 10.0 | uM | LJP6 | 3 | B19 | 72 | hr | 1476 | 797 | 3694 | 0.2158 | -0.3066 |
| MCF7 | Mitoxantrone | 10.0 | uM | LJP6 | 2 | C19 | 72 | hr | 1235 | 344 | 4156 | 0.0828 | -0.3052 |
| SK-BR-3 | GSK1059615 | 10.0 | uM | LJP5 | 3 | E01 | 72 | hr | 1476 | 801 | 3694 | 0.2168 | -0.3047 |
| SK-BR-3 | SNS-032 | 3.33 | uM | LJP6 | 1 | H14 | 72 | hr | 1476 | 801 | 3694 | 0.2168 | -0.3047 |