LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MCF7 SB590885
1.11
uM
LJP5
 3
L15
 72
hr
 1235 5144 4156 1.2377 1.3382
SK-BR-3 XL147
3.33
uM
LJP5
 1
G08
 72
hr
 1476 4575 3694 1.2385 1.3973
BT-20 PD173074
3.33
uM
LJP6
 2
I08
 72
hr
 1657 6819 5505 1.2385 1.3413
Hs 578T SB590885
3.33
uM
LJP5
 3
L14
 72
hr
 929 4003 3228 1.2401 1.3371
SK-BR-3 XL147
0.37
uM
LJP5
 1
G10
 72
hr
 1476 4585 3694 1.2412 1.4018
MCF7 TWS119
0.04
uM
LJP5
 3
M06
 72
hr
 1235 5168 4156 1.2435 1.3464
Hs 578T Sorafenib
1.11
uM
LJP6
 1
B09
 72
hr
 929 4036 3228 1.2503 1.3515
SK-BR-3 PD173074
0.04
uM
LJP6
 3
I12
 72
hr
 1476 4626 3694 1.2523 1.4203
Hs 578T Sorafenib
1.11
uM
LJP6
 3
B09
 72
hr
 929 4045 3228 1.2531 1.3554
MCF7 CP466722
0.37
uM
LJP5
 2
I10
 72
hr
 1235 5225 4156 1.2572 1.3659
MCF7 SU11274
0.04
uM
LJP5
 3
J12
 72
hr
 1235 5229 4156 1.2581 1.3673
BT-20 Enzastaurin
10.0
uM
LJP5
 2
D13
 72
hr
 1657 6961 5505 1.2643 1.3782
BT-20 Enzastaurin
10.0
uM
LJP5
 3
D13
 72
hr
 1657 6961 5505 1.2643 1.3782
BT-20 Enzastaurin
3.33
uM
LJP5
 3
D14
 72
hr
 1657 6985 5505 1.2687 1.3844
MCF7 PIK-93
0.12
uM
LJP5
 2
K17
 72
hr
 1235 5275 4156 1.2692 1.3831
Hs 578T Sorafenib
1.11
uM
LJP6
 2
B09
 72
hr
 929 4101 3228 1.2704 1.3797
MCF7 PIK-93
0.37
uM
LJP5
 3
K16
 72
hr
 1235 5327 4156 1.2817 1.4009
MCF7 Pelitinib
0.12
uM
LJP5
 3
I17
 72
hr
 1235 5374 4156 1.2930 1.4170
SK-BR-3 XL147
1.11
uM
LJP5
 1
G09
 72
hr
 1476 4824 3694 1.3059 1.5096
MCF7 LDN-193189
0.04
uM
LJP5
 3
G06
 72
hr
 1235 5439 4156 1.3087 1.4392