LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 R406
1.11
uM
LJP6
 1
C15
 72
hr
 868 3082 3486 0.8840 0.8456
MDA-MB-231 R406
1.11
uM
LJP6
 2
C15
 72
hr
 868 2739 3486 0.7856 0.7146
MDA-MB-231 R406
1.11
uM
LJP6
 3
C15
 72
hr
 868 2562 3486 0.7349 0.6469
MDA-MB-231 Pictilisib
1.11
uM
LJP6
 1
D21
 72
hr
 868 2369 3486 0.6795 0.5732
MDA-MB-231 Pictilisib
1.11
uM
LJP6
 2
D21
 72
hr
 868 2681 3486 0.7690 0.6924
MDA-MB-231 Pictilisib
1.11
uM
LJP6
 3
D21
 72
hr
 868 2577 3486 0.7392 0.6527
MDA-MB-231 Gefitinib
1.11
uM
LJP6
 1
N09
 72
hr
 868 3614 3486 1.0366 1.0487
MDA-MB-231 Gefitinib
1.11
uM
LJP6
 2
N09
 72
hr
 868 3769 3486 1.0811 1.1079
MDA-MB-231 Gefitinib
1.11
uM
LJP6
 3
N09
 72
hr
 868 3990 3486 1.1444 1.1923
MDA-MB-231 Geldanamycin
1.11
uM
LJP5
 1
O03
 72
hr
 868 1116 3486 0.3201 0.0947
MDA-MB-231 Geldanamycin
1.11
uM
LJP5
 2
O03
 72
hr
 868 1012 3486 0.2903 0.0550
MDA-MB-231 Geldanamycin
1.11
uM
LJP5
 3
O03
 72
hr
 868 1058 3486 0.3035 0.0725
MDA-MB-231 Geldanamycin
1.11
uM
LJP6
 1
O03
 72
hr
 868 1110 3486 0.3184 0.0924
MDA-MB-231 Geldanamycin
1.11
uM
LJP6
 2
O03
 72
hr
 868 1271 3486 0.3646 0.1539
MDA-MB-231 Geldanamycin
1.11
uM
LJP6
 3
O03
 72
hr
 868 1135 3486 0.3256 0.1019
MDA-MB-231 GSK1059615
1.11
uM
LJP5
 1
E03
 72
hr
 868 1653 3486 0.4741 0.2998
MDA-MB-231 GSK1059615
1.11
uM
LJP5
 2
E03
 72
hr
 868 1602 3486 0.4595 0.2803
MDA-MB-231 GSK1059615
1.11
uM
LJP5
 3
E03
 72
hr
 868 1758 3486 0.5043 0.3399
MDA-MB-231 GSK1059615
1.11
uM
LJP6
 1
C03
 72
hr
 868 1835 3486 0.5263 0.3693
MDA-MB-231 GSK1059615
1.11
uM
LJP6
 2
C03
 72
hr
 868 2000 3486 0.5737 0.4323
MDA-MB-231 GSK1059615
1.11
uM
LJP6
 3
C03
 72
hr
 868 1924 3486 0.5519 0.4033
MDA-MB-231 GSK1904529A
1.11
uM
LJP6
 1
H21
 72
hr
 868 3310 3486 0.9494 0.9326
MDA-MB-231 GSK1904529A
1.11
uM
LJP6
 2
H21
 72
hr
 868 3203 3486 0.9187 0.8918
MDA-MB-231 GSK1904529A
1.11
uM
LJP6
 3
H21
 72
hr
 868 3183 3486 0.9130 0.8841
MDA-MB-231 Omipalisib
1.11
uM
LJP6
 1
N03
 72
hr
 868 904 3486 0.2593 0.0137