LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 Mitoxantrone
0.12
uM
LJP6
 3
C23
 72
hr
 868 848 3486 0.2432 -0.0077
MDA-MB-231 MK2206
0.12
uM
LJP6
 1
F05
 72
hr
 868 3095 3486 0.8877 0.8505
MDA-MB-231 MK2206
0.12
uM
LJP6
 2
F05
 72
hr
 868 2890 3486 0.8289 0.7722
MDA-MB-231 MK2206
0.12
uM
LJP6
 3
F05
 72
hr
 868 3291 3486 0.9440 0.9254
MDA-MB-231 Neratinib
0.12
uM
LJP5
 1
A17
 72
hr
 868 2358 3486 0.6763 0.5690
MDA-MB-231 Neratinib
0.12
uM
LJP5
 2
A17
 72
hr
 868 2438 3486 0.6993 0.5996
MDA-MB-231 Neratinib
0.12
uM
LJP5
 3
A17
 72
hr
 868 2568 3486 0.7366 0.6492
MDA-MB-231 Nilotinib
0.12
uM
LJP5
 1
N17
 72
hr
 868 2580 3486 0.7400 0.6538
MDA-MB-231 Nilotinib
0.12
uM
LJP5
 2
N17
 72
hr
 868 2806 3486 0.8048 0.7401
MDA-MB-231 Nilotinib
0.12
uM
LJP5
 3
N17
 72
hr
 868 2971 3486 0.8522 0.8032
MDA-MB-231 Nintedanib
0.12
uM
LJP6
 1
H05
 72
hr
 868 3249 3486 0.9319 0.9093
MDA-MB-231 Nintedanib
0.12
uM
LJP6
 2
H05
 72
hr
 868 3849 3486 1.1040 1.1385
MDA-MB-231 Nintedanib
0.12
uM
LJP6
 3
H05
 72
hr
 868 3824 3486 1.0968 1.1289
MDA-MB-231 NU7441
0.12
uM
LJP5
 1
C11
 72
hr
 868 3336 3486 0.9569 0.9426
MDA-MB-231 NU7441
0.12
uM
LJP5
 2
C11
 72
hr
 868 2964 3486 0.8502 0.8005
MDA-MB-231 NU7441
0.12
uM
LJP5
 3
C11
 72
hr
 868 3528 3486 1.0119 1.0159
MDA-MB-231 Dactolisib
0.12
uM
LJP5
 1
M17
 72
hr
 868 1697 3486 0.4868 0.3166
MDA-MB-231 Dactolisib
0.12
uM
LJP5
 2
M17
 72
hr
 868 1914 3486 0.5490 0.3995
MDA-MB-231 Dactolisib
0.12
uM
LJP5
 3
M17
 72
hr
 868 1823 3486 0.5229 0.3647
MDA-MB-231 NVP-TAE684
0.12
uM
LJP6
 1
K17
 72
hr
 868 2158 3486 0.6190 0.4926
MDA-MB-231 NVP-TAE684
0.12
uM
LJP6
 2
K17
 72
hr
 868 2464 3486 0.7068 0.6095
MDA-MB-231 NVP-TAE684
0.12
uM
LJP6
 3
K17
 72
hr
 868 2310 3486 0.6626 0.5507
MDA-MB-231 Palbociclib
0.12
uM
LJP6
 1
E17
 72
hr
 868 2447 3486 0.7019 0.6030
MDA-MB-231 Palbociclib
0.12
uM
LJP6
 2
E17
 72
hr
 868 2402 3486 0.6890 0.5858
MDA-MB-231 Palbociclib
0.12
uM
LJP6
 3
E17
 72
hr
 868 2166 3486 0.6213 0.4957