LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 NVP-TAE684
0.04
uM
LJP6
 2
K18
 72
hr
 868 3206 3486 0.9196 0.8929
MDA-MB-231 NVP-TAE684
0.04
uM
LJP6
 3
K18
 72
hr
 868 3190 3486 0.9150 0.8868
MDA-MB-231 Palbociclib
0.04
uM
LJP6
 1
E18
 72
hr
 868 2687 3486 0.7707 0.6947
MDA-MB-231 Palbociclib
0.04
uM
LJP6
 2
E18
 72
hr
 868 2760 3486 0.7917 0.7226
MDA-MB-231 Palbociclib
0.04
uM
LJP6
 3
E18
 72
hr
 868 2674 3486 0.7670 0.6897
MDA-MB-231 PD0325901
0.04
uM
LJP5
 1
C06
 72
hr
 868 2068 3486 0.5932 0.4583
MDA-MB-231 PD0325901
0.04
uM
LJP5
 2
C06
 72
hr
 868 2184 3486 0.6264 0.5026
MDA-MB-231 PD0325901
0.04
uM
LJP5
 3
C06
 72
hr
 868 2118 3486 0.6075 0.4774
MDA-MB-231 PD0325901
0.04
uM
LJP6
 1
E06
 72
hr
 868 1922 3486 0.5513 0.4025
MDA-MB-231 PD0325901
0.04
uM
LJP6
 2
E06
 72
hr
 868 2293 3486 0.6577 0.5442
MDA-MB-231 PD0325901
0.04
uM
LJP6
 3
E06
 72
hr
 868 2397 3486 0.6875 0.5839
MDA-MB-231 PD173074
0.04
uM
LJP6
 1
I12
 72
hr
 868 3982 3486 1.1422 1.1893
MDA-MB-231 PD173074
0.04
uM
LJP6
 2
I12
 72
hr
 868 4166 3486 1.1949 1.2596
MDA-MB-231 PD173074
0.04
uM
LJP6
 3
I12
 72
hr
 868 4106 3486 1.1777 1.2366
MDA-MB-231 PD184352
0.04
uM
LJP5
 1
L12
 72
hr
 868 3408 3486 0.9775 0.9701
MDA-MB-231 PD184352
0.04
uM
LJP5
 2
L12
 72
hr
 868 3714 3486 1.0653 1.0869
MDA-MB-231 PD184352
0.04
uM
LJP5
 3
L12
 72
hr
 868 3639 3486 1.0438 1.0583
MDA-MB-231 Pelitinib
0.04
uM
LJP5
 1
I18
 72
hr
 868 3879 3486 1.1126 1.1499
MDA-MB-231 Pelitinib
0.04
uM
LJP5
 2
I18
 72
hr
 868 3816 3486 1.0945 1.1259
MDA-MB-231 Pelitinib
0.04
uM
LJP5
 3
I18
 72
hr
 868 3528 3486 1.0119 1.0159
MDA-MB-231 PF431396
0.04
uM
LJP5
 1
E12
 72
hr
 868 3308 3486 0.9488 0.9319
MDA-MB-231 PF431396
0.04
uM
LJP5
 2
E12
 72
hr
 868 3323 3486 0.9531 0.9376
MDA-MB-231 PF431396
0.04
uM
LJP5
 3
E12
 72
hr
 868 3357 3486 0.9629 0.9506
MDA-MB-231 PF477736
0.04
uM
LJP5
 1
J24
 72
hr
 868 2726 3486 0.7819 0.7096
MDA-MB-231 PF477736
0.04
uM
LJP5
 2
J24
 72
hr
 868 3418 3486 0.9804 0.9739