LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
BT-20 Buparlisib
0.37
uM
LJP5
2
H04
72
hr
1657 3613 5505 0.6562 0.5081
BT-20 Buparlisib
0.37
uM
LJP5
3
H04
72
hr
1657 3839 5505 0.6973 0.5669
BT-20 BX-912
0.37
uM
LJP5
1
L22
72
hr
1657 5729 5505 1.0406 1.0580
BT-20 BX-912
0.37
uM
LJP5
2
L22
72
hr
1657 4970 5505 0.9027 0.8608
BT-20 BX-912
0.37
uM
LJP5
3
L22
72
hr
1657 5670 5505 1.0298 1.0427
BT-20 Canertinib
0.37
uM
LJP6
1
H10
72
hr
1657 4496 5505 0.8166 0.7376
BT-20 Canertinib
0.37
uM
LJP6
2
H10
72
hr
1657 4613 5505 0.8379 0.7680
BT-20 Canertinib
0.37
uM
LJP6
3
H10
72
hr
1657 4597 5505 0.8350 0.7639
BT-20 Celastrol
0.37
uM
LJP6
1
G10
72
hr
1657 4489 5505 0.8153 0.7358
BT-20 Celastrol
0.37
uM
LJP6
2
G10
72
hr
1657 4557 5505 0.8277 0.7535
BT-20 Celastrol
0.37
uM
LJP6
3
G10
72
hr
1657 4778 5505 0.8678 0.8109
BT-20 CGP60474
0.37
uM
LJP5
1
F04
72
hr
1657 1481 5505 0.2690 -0.0459
BT-20 CGP60474
0.37
uM
LJP5
2
F04
72
hr
1657 1619 5505 0.2941 -0.0101
BT-20 CGP60474
0.37
uM
LJP5
3
F04
72
hr
1657 1524 5505 0.2768 -0.0348
BT-20 CGP60474
0.37
uM
LJP6
1
G04
72
hr
1657 1047 5505 0.1902 -0.1587
BT-20 CGP60474
0.37
uM
LJP6
2
G04
72
hr
1657 1119 5505 0.2033 -0.1400
BT-20 CGP60474
0.37
uM
LJP6
3
G04
72
hr
1657 932 5505 0.1693 -0.1886
BT-20 CHIR-99021
0.37
uM
LJP6
1
P16
72
hr
1657 5438 5505 0.9877 0.9824
BT-20 CHIR-99021
0.37
uM
LJP6
2
P16
72
hr
1657 5574 5505 1.0124 1.0178
BT-20 CHIR-99021
0.37
uM
LJP6
3
P16
72
hr
1657 5522 5505 1.0030 1.0042
BT-20 CP724714
0.37
uM
LJP5
1
A10
72
hr
1657 5057 5505 0.9185 0.8834
BT-20 CP724714
0.37
uM
LJP5
2
A10
72
hr
1657 4815 5505 0.8746 0.8205
BT-20 CP724714
0.37
uM
LJP5
3
A10
72
hr
1657 4799 5505 0.8717 0.8164
BT-20 CP466722
0.37
uM
LJP5
1
I10
72
hr
1657 5858 5505 1.0640 1.0916
BT-20 CP466722
0.37
uM
LJP5
2
I10
72
hr
1657 5900 5505 1.0716 1.1025