LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
BT-20 Seliciclib
0.04
uM
LJP5
3
J06
72
hr
1657 5764 5505 1.0469 1.0671
BT-20 Ruxolitinib
0.04
uM
LJP5
1
O18
72
hr
1657 5046 5505 0.9165 0.8805
BT-20 Ruxolitinib
0.04
uM
LJP5
2
O18
72
hr
1657 5411 5505 0.9828 0.9754
BT-20 Ruxolitinib
0.04
uM
LJP5
3
O18
72
hr
1657 5130 5505 0.9318 0.9024
BT-20 XL147
0.04
uM
LJP5
1
G12
72
hr
1657 5908 5505 1.0731 1.1046
BT-20 XL147
0.04
uM
LJP5
2
G12
72
hr
1657 5828 5505 1.0585 1.0838
BT-20 XL147
0.04
uM
LJP5
3
G12
72
hr
1657 5720 5505 1.0389 1.0557
BT-20 Saracatinib
0.04
uM
LJP6
1
D12
72
hr
1657 5549 5505 1.0079 1.0113
BT-20 Saracatinib
0.04
uM
LJP6
2
D12
72
hr
1657 5361 5505 0.9737 0.9624
BT-20 Saracatinib
0.04
uM
LJP6
3
D12
72
hr
1657 6035 5505 1.0961 1.1376
BT-20 Selumetinib
0.04
uM
LJP6
1
M12
72
hr
1657 5774 5505 1.0487 1.0697
BT-20 Selumetinib
0.04
uM
LJP6
2
M12
72
hr
1657 6445 5505 1.1706 1.2441
BT-20 Selumetinib
0.04
uM
LJP6
3
M12
72
hr
1657 6159 5505 1.1187 1.1698
BT-20 Sirolimus
0.04
uM
LJP6
1
L18
72
hr
1657 3582 5505 0.6506 0.5001
BT-20 Sirolimus
0.04
uM
LJP6
2
L18
72
hr
1657 3506 5505 0.6368 0.4803
BT-20 Sirolimus
0.04
uM
LJP6
3
L18
72
hr
1657 3489 5505 0.6337 0.4759
BT-20 Sorafenib
0.04
uM
LJP6
1
B12
72
hr
1657 5124 5505 0.9307 0.9008
BT-20 Sorafenib
0.04
uM
LJP6
2
B12
72
hr
1657 4581 5505 0.8321 0.7597
BT-20 Sorafenib
0.04
uM
LJP6
3
B12
72
hr
1657 5663 5505 1.0286 1.0409
BT-20 SU11274
0.04
uM
LJP5
1
J12
72
hr
1657 5572 5505 1.0120 1.0172
BT-20 SU11274
0.04
uM
LJP5
2
J12
72
hr
1657 5838 5505 1.0604 1.0864
BT-20 SU11274
0.04
uM
LJP5
3
J12
72
hr
1657 5648 5505 1.0259 1.0370
BT-20 Fedratinib
0.04
uM
LJP5
1
L06
72
hr
1657 5674 5505 1.0306 1.0437
BT-20 Fedratinib
0.04
uM
LJP5
2
L06
72
hr
1657 6014 5505 1.0923 1.1321
BT-20 Fedratinib
0.04
uM
LJP5
3
L06
72
hr
1657 5362 5505 0.9739 0.9627