LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | AZD7762 | 3.33 | uM | LJP6 | 1 | L02 | 72 | hr | 513 | 978 | 10401 | 0.0940 | 0.0470 |
| MCF 10A | AZD7762 | 3.33 | uM | LJP6 | 2 | L02 | 72 | hr | 513 | 963 | 10401 | 0.0926 | 0.0455 |
| MCF 10A | AZD7762 | 3.33 | uM | LJP6 | 3 | L02 | 72 | hr | 513 | 869 | 10401 | 0.0835 | 0.0360 |
| MCF 10A | AZD7762 | 10.0 | uM | LJP6 | 1 | L01 | 72 | hr | 513 | 352 | 10401 | 0.0338 | -0.0163 |
| MCF 10A | AZD7762 | 10.0 | uM | LJP6 | 2 | L01 | 72 | hr | 513 | 375 | 10401 | 0.0361 | -0.0140 |
| MCF 10A | AZD7762 | 10.0 | uM | LJP6 | 3 | L01 | 72 | hr | 513 | 334 | 10401 | 0.0321 | -0.0181 |
| MCF7 | AZD7762 | 0.04 | uM | LJP6 | 1 | L06 | 72 | hr | 1235 | 1960 | 4156 | 0.4716 | 0.2481 |
| MCF7 | AZD7762 | 0.04 | uM | LJP6 | 2 | L06 | 72 | hr | 1235 | 1919 | 4156 | 0.4617 | 0.2341 |
| MCF7 | AZD7762 | 0.04 | uM | LJP6 | 3 | L06 | 72 | hr | 1235 | 1833 | 4156 | 0.4410 | 0.2046 |
| MCF7 | AZD7762 | 0.12 | uM | LJP6 | 1 | L05 | 72 | hr | 1235 | 1766 | 4156 | 0.4249 | 0.1817 |
| MCF7 | AZD7762 | 0.12 | uM | LJP6 | 2 | L05 | 72 | hr | 1235 | 1688 | 4156 | 0.4061 | 0.1550 |
| MCF7 | AZD7762 | 0.12 | uM | LJP6 | 3 | L05 | 72 | hr | 1235 | 1665 | 4156 | 0.4006 | 0.1471 |
| MCF7 | AZD7762 | 0.37 | uM | LJP6 | 1 | L04 | 72 | hr | 1235 | 1658 | 4156 | 0.3989 | 0.1447 |
| MCF7 | AZD7762 | 0.37 | uM | LJP6 | 2 | L04 | 72 | hr | 1235 | 1507 | 4156 | 0.3626 | 0.0930 |
| MCF7 | AZD7762 | 0.37 | uM | LJP6 | 3 | L04 | 72 | hr | 1235 | 1467 | 4156 | 0.3530 | 0.0793 |
| MCF7 | AZD7762 | 1.11 | uM | LJP6 | 1 | L03 | 72 | hr | 1235 | 1294 | 4156 | 0.3113 | 0.0201 |
| MCF7 | AZD7762 | 1.11 | uM | LJP6 | 2 | L03 | 72 | hr | 1235 | 1272 | 4156 | 0.3061 | 0.0125 |
| MCF7 | AZD7762 | 1.11 | uM | LJP6 | 3 | L03 | 72 | hr | 1235 | 1365 | 4156 | 0.3284 | 0.0444 |
| MCF7 | AZD7762 | 3.33 | uM | LJP6 | 1 | L02 | 72 | hr | 1235 | 1118 | 4156 | 0.2690 | -0.0402 |
| MCF7 | AZD7762 | 3.33 | uM | LJP6 | 2 | L02 | 72 | hr | 1235 | 993 | 4156 | 0.2389 | -0.0830 |
| MCF7 | AZD7762 | 3.33 | uM | LJP6 | 3 | L02 | 72 | hr | 1235 | 1060 | 4156 | 0.2550 | -0.0600 |
| MCF7 | AZD7762 | 10.0 | uM | LJP6 | 1 | L01 | 72 | hr | 1235 | 728 | 4156 | 0.1752 | -0.1737 |
| MCF7 | AZD7762 | 10.0 | uM | LJP6 | 2 | L01 | 72 | hr | 1235 | 796 | 4156 | 0.1915 | -0.1504 |
| MCF7 | AZD7762 | 10.0 | uM | LJP6 | 3 | L01 | 72 | hr | 1235 | 773 | 4156 | 0.1860 | -0.1583 |
| MDA-MB-231 | AZD7762 | 0.04 | uM | LJP6 | 1 | L06 | 72 | hr | 868 | 1815 | 3486 | 0.5206 | 0.3616 |