LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
BT-20 Seliciclib
10.0
uM
LJP5
 3
J01
 72
hr
 1657 1957 5505 0.3555 0.0778
BT-20 Ruxolitinib
10.0
uM
LJP5
 1
O13
 72
hr
 1657 4093 5505 0.7434 0.6329
BT-20 Ruxolitinib
10.0
uM
LJP5
 2
O13
 72
hr
 1657 3943 5505 0.7162 0.5939
BT-20 Ruxolitinib
10.0
uM
LJP5
 3
O13
 72
hr
 1657 3918 5505 0.7116 0.5874
BT-20 XL147
10.0
uM
LJP5
 1
G07
 72
hr
 1657 2184 5505 0.3967 0.1368
BT-20 XL147
10.0
uM
LJP5
 2
G07
 72
hr
 1657 2146 5505 0.3898 0.1269
BT-20 XL147
10.0
uM
LJP5
 3
G07
 72
hr
 1657 2225 5505 0.4041 0.1474
BT-20 Saracatinib
10.0
uM
LJP6
 1
D07
 72
hr
 1657 1969 5505 0.3576 0.0809
BT-20 Saracatinib
10.0
uM
LJP6
 2
D07
 72
hr
 1657 2272 5505 0.4127 0.1596
BT-20 Saracatinib
10.0
uM
LJP6
 3
D07
 72
hr
 1657 2398 5505 0.4356 0.1924
BT-20 Selumetinib
10.0
uM
LJP6
 1
M07
 72
hr
 1657 5484 5505 0.9961 0.9944
BT-20 Selumetinib
10.0
uM
LJP6
 2
M07
 72
hr
 1657 5672 5505 1.0302 1.0432
BT-20 Selumetinib
10.0
uM
LJP6
 3
M07
 72
hr
 1657 5096 5505 0.9256 0.8935
BT-20 Sirolimus
10.0
uM
LJP6
 1
L13
 72
hr
 1657 3731 5505 0.6777 0.5388
BT-20 Sirolimus
10.0
uM
LJP6
 2
L13
 72
hr
 1657 3799 5505 0.6900 0.5565
BT-20 Sirolimus
10.0
uM
LJP6
 3
L13
 72
hr
 1657 3867 5505 0.7024 0.5741
BT-20 Sorafenib
10.0
uM
LJP6
 1
B07
 72
hr
 1657 2657 5505 0.4826 0.2597
BT-20 Sorafenib
10.0
uM
LJP6
 2
B07
 72
hr
 1657 2647 5505 0.4808 0.2571
BT-20 Sorafenib
10.0
uM
LJP6
 3
B07
 72
hr
 1657 3172 5505 0.5761 0.3935
BT-20 SU11274
10.0
uM
LJP5
 1
J07
 72
hr
 1657 2102 5505 0.3818 0.1155
BT-20 SU11274
10.0
uM
LJP5
 2
J07
 72
hr
 1657 2153 5505 0.3911 0.1287
BT-20 SU11274
10.0
uM
LJP5
 3
J07
 72
hr
 1657 2026 5505 0.3680 0.0957
BT-20 Fedratinib
10.0
uM
LJP5
 1
L01
 72
hr
 1657 1722 5505 0.3128 0.0167
BT-20 Fedratinib
10.0
uM
LJP5
 2
L01
 72
hr
 1657 1562 5505 0.2837 -0.0249
BT-20 Fedratinib
10.0
uM
LJP5
 3
L01
 72
hr
 1657 1822 5505 0.3309 0.0427