Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-5
 9.5 56
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-5
 12.0 57
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-5
 10.5 68
RA1869 IL-1 alpha 100
ng/mL
 3
IL-5
 11.0 75
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-5
 10.0 65
N2759 IL-1 alpha 100
ng/mL
 3
IL-5
 11.0 73
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-5
 10.0 83
RA1931 IL-1 alpha 100
ng/mL
 3
IL-5
 11.0 67
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-5
 9.0 60
N2586 IL-1 alpha 100
ng/mL
 3
IL-5
 10.0 61
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-5
 11.0 62
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-5
 12.0 67
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-5
 9.0 81
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-5
 11.0 64
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-5
 10.0 74
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-5
 9.0 92
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-5
 8.0 83
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-5
 10.0 82
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-5
 11.0 72
RA1869 TNF-a 100
ng/mL
 3
IL-5
 13.5 72
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-5
 11.0 77
N2759 TNF-a 100
ng/mL
 3
IL-5
 9.0 55
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-5
 10.0 74
RA1931 TNF-a 100
ng/mL
 3
IL-5
 10.0 67
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-5
 11.0 78