Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
TRAIL
 41.0 62
RA1869 IL-1 alpha 100
ng/mL
 1
TRAIL
 42.0 46
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
TRAIL
 47.5 50
N2759 IL-1 alpha 100
ng/mL
 1
TRAIL
 40.0 46
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
TRAIL
 48.0 66
RA1931 IL-1 alpha 100
ng/mL
 1
TRAIL
 46.0 51
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
TRAIL
 55.0 44
N2586 IL-1 alpha 100
ng/mL
 1
TRAIL
 53.5 48
RA1869 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
TRAIL
 21.0 51
RA1869 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
TRAIL
 16.0 69
N2759 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
TRAIL
 23.0 62
N2759 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
TRAIL
 21.0 70
RA1931 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
TRAIL
 13.0 45
RA1931 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
TRAIL
 19.0 50
N2586 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
TRAIL
 23.0 69
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
TRAIL
 18.0 63
RA1869 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
TRAIL
 18.5 54
RA1869 Poly(I:C) 2
ug/mL
 1
TRAIL
 18.0 47
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
TRAIL
 21.0 61
N2759 Poly(I:C) 2
ug/mL
 1
TRAIL
 22.0 62
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
TRAIL
 17.0 57
RA1931 Poly(I:C) 2
ug/mL
 1
TRAIL
 20.0 52
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
TRAIL
 20.0 67
N2586 Poly(I:C) 2
ug/mL
 1
TRAIL
 22.0 73
RA1869 5z-7-oxozeaenol 0.6
uM
 1
TRAIL
 17.5 68