Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 PH-797804 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL-17
 69.0 58
RA1869 1
IL-17
 39.0 54
N2759 1
IL-17
 34.0 63
RA1931 1
IL-17
 32.5 70
N2586 1
IL-17
 33.0 75
RA1869 JNK-IN-8 3.0
uM
 1
IL-17
 34.0 67
RA1869 PH-797804 0.6
uM
 1
IL-17
 36.5 66
N2759 JNK-IN-8 3.0
uM
 1
IL-17
 35.0 57
N2759 PH-797804 0.6
uM
 1
IL-17
 40.0 51
RA1931 JNK-IN-8 3.0
uM
 1
IL-17
 38.0 49
RA1931 PH-797804 0.6
uM
 1
IL-17
 36.0 54
N2586 JNK-IN-8 3.0
uM
 1
IL-17
 32.0 44
N2586 PH-797804 0.6
uM
 1
IL-17
 36.0 57
RA1869 5z-7-oxozeaenol 0.6
uM
 1
IL-17
 36.5 70
RA1869 IKK16 2.0
uM
 1
IL-17
 39.5 62
N2759 5z-7-oxozeaenol 0.6
uM
 1
IL-17
 25.0 65
N2759 IKK16 2.0
uM
 1
IL-17
 34.0 69
RA1931 5z-7-oxozeaenol 0.6
uM
 1
IL-17
 34.0 73
RA1931 IKK16 2.0
uM
 1
IL-17
 24.5 82
N2586 5z-7-oxozeaenol 0.6
uM
 1
IL-17
 33.0 72
N2586 IKK16 2.0
uM
 1
IL-17
 40.0 74
RA1869 Tofacitinib 0.3
uM
 1
IL-17
 33.5 56
RA1869 1
IL-17
 36.0 65
N2759 Tofacitinib 0.3
uM
 1
IL-17
 32.0 70
N2759 1
IL-17
 38.0 53