Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA1869 | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 132.0 | 60 | ||||
| N2759 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 98.0 | 40 | |
| N2759 | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 106.0 | 46 | ||||
| RA1931 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 147.0 | 53 | |
| RA1931 | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 78.0 | 59 | ||||
| N2586 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 130.0 | 52 | |
| N2586 | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 79.0 | 55 | ||||
| RA1869 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 53.0 | 54 | |
| RA1869 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 83.0 | 57 | |
| N2759 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 34.0 | 63 | |
| N2759 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 74.0 | 55 | |
| RA1931 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 73.0 | 38 | |
| RA1931 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 100.5 | 42 | |
| N2586 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 93.0 | 58 | |
| N2586 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 69.0 | 44 | |
| RA1869 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 117.5 | 38 | |
| RA1869 | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 144.0 | 49 | ||||
| N2759 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 134.0 | 44 | |
| N2759 | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 116.0 | 34 | ||||
| RA1931 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 150.5 | 40 | |
| RA1931 | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 83.0 | 40 | ||||
| N2586 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 164.0 | 41 | |
| N2586 | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 106.5 | 46 | ||||
| RA1869 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 40.5 | 64 | |
| RA1869 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 62.0 | 57 |