Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1869 5z-7-oxozeaenol 0.6
uM
 1
IL-12 (p70)
 54.0 67
RA1869 IKK16 2.0
uM
 1
IL-12 (p70)
 87.0 47
N2759 5z-7-oxozeaenol 0.6
uM
 1
IL-12 (p70)
 41.5 62
N2759 IKK16 2.0
uM
 1
IL-12 (p70)
 69.0 66
RA1931 5z-7-oxozeaenol 0.6
uM
 1
IL-12 (p70)
 66.5 58
RA1931 IKK16 2.0
uM
 1
IL-12 (p70)
 53.0 61
N2586 5z-7-oxozeaenol 0.6
uM
 1
IL-12 (p70)
 74.0 69
N2586 IKK16 2.0
uM
 1
IL-12 (p70)
 55.5 56
RA1869 Tofacitinib 0.3
uM
 1
IL-12 (p70)
 72.5 60
RA1869 1
IL-12 (p70)
 111.5 54
N2759 Tofacitinib 0.3
uM
 1
IL-12 (p70)
 72.0 67
N2759 1
IL-12 (p70)
 94.0 51
RA1931 Tofacitinib 0.3
uM
 1
IL-12 (p70)
 117.0 49
RA1931 1
IL-12 (p70)
 60.5 48
N2586 Tofacitinib 0.3
uM
 1
IL-12 (p70)
 107.0 45
N2586 1
IL-12 (p70)
 86.0 48
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL-12 (p70)
 85.0 57
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-12 (p70)
 92.5 56
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL-12 (p70)
 69.0 67
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-12 (p70)
 56.0 64
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL-12 (p70)
 65.0 59
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-12 (p70)
 106.0 51
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL-12 (p70)
 89.0 59
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-12 (p70)
 93.0 54
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-12 (p70)
 127.0 62